%0 Case Reports
%T Immunotherapy combined with targeted therapy in advanced small cell carcinoma of the ovary of hypercalcemic type: A case of overall survival lasting for over 5 years.
%A Gao Y
%A Zang L
%A Ye Y
%A Ma F
%A Kang M
%A Zheng K
%A Kang Y
%A Wang H
%A Xu C
%J Eur J Obstet Gynecol Reprod Biol
%V 297
%N 0
%D 2024 Jun 6
%M 38604920
%F 2.831
%R 10.1016/j.ejogrb.2024.04.001
%X Small cell carcinoma of the ovary, hypercalcemic type (SCCOHT) is a rare but highly aggressive ovarian malignant neoplasm lacking a unified clinical management process. Most patients are diagnosed at an advanced stage and have an extremely poor prognosis with an overall probability of survival less than 10 %. Here, we describe the case of a patient with advanced SCCOHT achieved a survival of over 5 years after receiving multiple cycles of immunotherapy combined with anti-angiogenic therapy or CDK4/6 inhibitors. At the same time, we also summarized the case reports and clinical trials of immunotherapy in SCCOHT.