Abstract:
Extraskeletal myxoid chondrosarcoma is a rare soft tissue tumour with a high local and distant metastasis rate and limited response to chemotherapy. Meckel\'s diverticulum is the most frequent congenital anomaly, and it is associated with a considerable risk of malignant transformation. In this case report, we describe a 50-year-old female patient with a history of extraskeletal myxoid chondrosarcoma of the lower limb and metastasis to the forearm who went to the emergency department with abdominal pain. The investigations revealed a caecal volvulus. A lesion in the middle third of the ileum was incidentally discovered and removed during surgery. Pathology examination revealed a Meckel\'s diverticulum adenocarcinoma, with metastasis of extraskeletal myxoid chondrosarcoma. Resection was complete; however, the patient had diffuse metastatic pulmonary disease and died eight months later due to disease progression. This mechanism of tumour-to-tumour metastasis is described in other locations, but, regarding the Meckel\'s diverticulum, this is a unique situation, previously unreported in the literature.
摘要:
骨外粘液样软骨肉瘤是一种罕见的软组织肿瘤,具有较高的局部和远处转移率,对化疗的反应有限。Meckel憩室是最常见的先天性异常,它与恶性转化的相当大的风险有关。在这个案例报告中,我们描述了一名50岁的女性患者,该患者有下肢骨外黏液样软骨肉瘤和前臂转移的病史,该患者因腹痛前往急诊科。调查发现盲肠扭转。在手术中偶然发现并切除了回肠中部三分之一的病变。病理检查发现Meckel憩室腺癌,伴有骨外黏液样软骨肉瘤转移。切除完成;然而,患者患有弥漫性转移性肺病,8个月后因疾病进展死亡.在其他地方描述了肿瘤到肿瘤转移的机制,但是,关于Meckel的憩室,这是一个独特的情况,以前在文献中没有报道。