PDF(Pubmed)
Abstract：
OBJECTIVE: To assess the impact of glaucoma on perceiving three-dimensional (3D) shapes based on monocular depth cues.
METHODS: Clinical observational study.
METHODS: Twenty glaucoma patients, subjected to binocular visual-field sensitivity (binocular-VFS) tests using a Humphrey Visual Field Analyzer, and 20 age-matched healthy volunteers, underwent two tasks: identifying the nearest vertex of a 3D shape using monocular shading (3D-SfS), texture (3D-SfT), or motion (3D-SfM) cues, and distinguishing elementary one-dimensional (1D) features of these cues. The association of the visual-field index (VFI) of binocular-VFS with 3D shape perception in glaucoma patients was also examined.
RESULTS: Glaucoma patients demonstrated reduced accuracy in distinguishing 1D luminance brightness and a larger \"error-in-depth\" between the perceived and actual depths for 3D-SfM and 3D-SfS compared to healthy volunteers. Six glaucoma patients with a 100% VFI for binocular-VFS exhibited a similar error-in-depth to the other fourteen glaucoma patients; they had a larger error-in-depth for 3D-SfM compared to healthy volunteers. No correlation between the error-in-depth values and the VFI values of binocular-VFS was observed.
CONCLUSIONS: The 3D shape perception in glaucoma patients varies based on the depth cue\'s characteristics. Impaired 1D discrimination and larger thresholds for 3D-SfM in glaucoma patients with a 100% VFI for binocular-VFS indicate more pronounced perceptual deficits of lower-level elementary features for 3D-SfS and higher-level visual processing of 3D shapes for 3D-SfM. The effects of the location and degree of binocular visual-field defects on 3D shape perception remain to be elucidated. Our research provides insights into the 3D shape extraction mechanism in glaucoma.
METHODS: Clinical observational study.
METHODS: Twenty glaucoma patients, subjected to binocular visual-field sensitivity (binocular-VFS) tests using a Humphrey Visual Field Analyzer, and 20 age-matched healthy volunteers, underwent two tasks: identifying the nearest vertex of a 3D shape using monocular shading (3D-SfS), texture (3D-SfT), or motion (3D-SfM) cues, and distinguishing elementary one-dimensional (1D) features of these cues. The association of the visual-field index (VFI) of binocular-VFS with 3D shape perception in glaucoma patients was also examined.
RESULTS: Glaucoma patients demonstrated reduced accuracy in distinguishing 1D luminance brightness and a larger \"error-in-depth\" between the perceived and actual depths for 3D-SfM and 3D-SfS compared to healthy volunteers. Six glaucoma patients with a 100% VFI for binocular-VFS exhibited a similar error-in-depth to the other fourteen glaucoma patients; they had a larger error-in-depth for 3D-SfM compared to healthy volunteers. No correlation between the error-in-depth values and the VFI values of binocular-VFS was observed.
CONCLUSIONS: The 3D shape perception in glaucoma patients varies based on the depth cue\'s characteristics. Impaired 1D discrimination and larger thresholds for 3D-SfM in glaucoma patients with a 100% VFI for binocular-VFS indicate more pronounced perceptual deficits of lower-level elementary features for 3D-SfS and higher-level visual processing of 3D shapes for 3D-SfM. The effects of the location and degree of binocular visual-field defects on 3D shape perception remain to be elucidated. Our research provides insights into the 3D shape extraction mechanism in glaucoma.
摘要：
目的：根据单眼深度线索评估青光眼对感知三维（3D）形状的影响。
方法：临床观察性研究。
方法：20例青光眼患者，使用Humphrey视野分析仪进行双目视野敏感度（双目VFS）测试，和20名年龄匹配的健康志愿者，经历了两个任务：使用单目阴影(3D-SfS)识别3D形状的最近顶点，纹理(3D-SfT),或运动(3D-SfM)提示，并区分这些线索的基本一维(1D)特征。还检查了双眼VFS的视野指数（VFI）与青光眼患者的3D形状感知的关联。
结果：与健康志愿者相比，青光眼患者在区分1D亮度亮度方面的准确性降低，3D-SfM和3D-SfS的感知深度和实际深度之间的“深度误差”更大。6例双眼VFS的VFI为100％的青光眼患者表现出与其他14例青光眼患者相似的深度误差；与健康志愿者相比，他们对3D-SfM的深度误差更大。在深度误差值和双眼VFS的VFI值之间没有观察到相关性。
结论：青光眼患者的3D形状感知根据深度提示的特征而变化。在双眼VFS为100％VFI的青光眼患者中，1D辨别能力受损和3D-SfM阈值较大，表明3D-SfS的低级基本特征的感知缺陷更为明显，3D-SfM的3D形状的高级视觉处理更为明显。双眼视野缺陷的位置和程度对3D形状感知的影响仍有待阐明。我们的研究为青光眼的3D形状提取机制提供了见解。
方法：临床观察性研究。
方法：20例青光眼患者，使用Humphrey视野分析仪进行双目视野敏感度（双目VFS）测试，和20名年龄匹配的健康志愿者，经历了两个任务：使用单目阴影(3D-SfS)识别3D形状的最近顶点，纹理(3D-SfT),或运动(3D-SfM)提示，并区分这些线索的基本一维(1D)特征。还检查了双眼VFS的视野指数（VFI）与青光眼患者的3D形状感知的关联。
结果：与健康志愿者相比，青光眼患者在区分1D亮度亮度方面的准确性降低，3D-SfM和3D-SfS的感知深度和实际深度之间的“深度误差”更大。6例双眼VFS的VFI为100％的青光眼患者表现出与其他14例青光眼患者相似的深度误差；与健康志愿者相比，他们对3D-SfM的深度误差更大。在深度误差值和双眼VFS的VFI值之间没有观察到相关性。
结论：青光眼患者的3D形状感知根据深度提示的特征而变化。在双眼VFS为100％VFI的青光眼患者中，1D辨别能力受损和3D-SfM阈值较大，表明3D-SfS的低级基本特征的感知缺陷更为明显，3D-SfM的3D形状的高级视觉处理更为明显。双眼视野缺陷的位置和程度对3D形状感知的影响仍有待阐明。我们的研究为青光眼的3D形状提取机制提供了见解。
