PDF(Pubmed)
Abstract：
Meningitis caused by Streptococcus gallolyticus subspecies (subsp.) pasteurianus is a rare complication with 14 cases reported in literature worldwide between 2003-2023, with the majority of the cases occurring before 4 weeks of life and with preceding symptoms. This is a case report of an infection without any preceding symptoms. A previously healthy 7-week-old boy presented to the hospital with a fever for 1 day. Blood and cerebrospinal fluid cultures ultimately grew Streptococcus gallolyticus subsp. pasteurianus. The magnetic resonance imaging was consistent with meningitis. The boy received 21 days of intravenous antibiotics before discharge. At subsequent visits, the boy had no neurological sequelae, normal hearing tests, and appeared to have met all developmental milestones. The older age of infant should not discount the differential diagnosis for meningitis, which may delay further work up such as a lumbar puncture. Group D streptococcus is an uncommon cause of infantile sepsis that can lead to several complications such as meningitis and bacteremia. In this case, the infant\'s subsequent post-meningitis clinical course has been unremarkable. The history of meningitis poses increased risk for abnormal neurodevelopmental outcome. This case study highlights the importance of keeping meningitis on the differential diagnosis for an infant with fever. If there is a concern for meningitis, further workup should be performed without delay.
摘要：
由溶胆链球菌亚种引起的脑膜炎（亚种。）巴氏菌是一种罕见的并发症，在2003年至2023年之间，全球文献报道了14例，大多数病例发生在生命4周之前，并且有先前的症状。这是一例没有任何先前症状的感染病例报告。一名先前健康的7周大男孩因发烧1天到医院就诊。血液和脑脊液培养物最终生长出溶胆链球菌亚种。巴氏杆菌.磁共振成像与脑膜炎一致。男孩在出院前接受了21天的静脉注射抗生素。在随后的访问中，这个男孩没有神经后遗症，正常的听力测试,似乎已经达到了所有的发展里程碑。婴儿年龄较大不应忽视脑膜炎的鉴别诊断，这可能会延迟进一步的工作，如腰椎穿刺。D组链球菌是婴儿败血症的罕见原因，可导致多种并发症，例如脑膜炎和菌血症。在这种情况下,婴儿随后的脑膜炎后临床过程并不显著。脑膜炎病史增加了神经发育异常的风险。此案例研究强调了在发热婴儿的鉴别诊断中保持脑膜炎的重要性。如果有脑膜炎的担忧,应毫不拖延地进行进一步的检查。
