PDF(Pubmed)
Abstract：
BACKGROUND: Limited studies have reported surgical outcomes that are defined by strict criteria following grade 2 or 3 socket reconstruction using an oral mucosal graft (OMG). We aimed to determine factors influencing surgical outcomes of anophthalmic socket reconstruction using OMG in patients with grade 2 or 3 socket contractures.
METHODS: Thirty-seven patients who underwent socket reconstruction with autologous OMG between January 2007 and December 2017 were retrospectively analyzed. The successful outcome was defined as an eye prosthesis wearing without experiencing displacement and the absence of any re-operations or additional surgeries following socket reconstruction. Factors affecting surgical outcomes were identified using multivariate analysis.
RESULTS: A total of 15 male and 22 female patients (mean age: 40.2 ± 17.2 years) were included. The median duration of socket contracture was 21.5 years. Grade 2 and 3 socket contractures, based on Tawfik\'s classification, were reported in 20 and 17 patients, respectively. Twenty-eight and eight patients underwent socket reconstruction using OMG alone and OMG combined with a hard palate graft, respectively. The success rates of grades 2 and 3 socket contracture reconstruction were 80.0% and 52.9%, respectively. Multivariate analysis demonstrated that only grade 3 contractures were predictive of worse outcomes. At the final visit (mean follow-up: 6.3 years), 34 patients (91.9%) could wear their eye prostheses.
CONCLUSIONS: Socket reconstruction using autologous OMG can provide acceptable results in grade 2 and 3 contractures; however, satisfactory results were more significantly reported in grade 2 than in grade 3 contractures.
METHODS: Thirty-seven patients who underwent socket reconstruction with autologous OMG between January 2007 and December 2017 were retrospectively analyzed. The successful outcome was defined as an eye prosthesis wearing without experiencing displacement and the absence of any re-operations or additional surgeries following socket reconstruction. Factors affecting surgical outcomes were identified using multivariate analysis.
RESULTS: A total of 15 male and 22 female patients (mean age: 40.2 ± 17.2 years) were included. The median duration of socket contracture was 21.5 years. Grade 2 and 3 socket contractures, based on Tawfik\'s classification, were reported in 20 and 17 patients, respectively. Twenty-eight and eight patients underwent socket reconstruction using OMG alone and OMG combined with a hard palate graft, respectively. The success rates of grades 2 and 3 socket contracture reconstruction were 80.0% and 52.9%, respectively. Multivariate analysis demonstrated that only grade 3 contractures were predictive of worse outcomes. At the final visit (mean follow-up: 6.3 years), 34 patients (91.9%) could wear their eye prostheses.
CONCLUSIONS: Socket reconstruction using autologous OMG can provide acceptable results in grade 2 and 3 contractures; however, satisfactory results were more significantly reported in grade 2 than in grade 3 contractures.
摘要：
背景：有限的研究报道了在使用口腔粘膜移植物（OMG）进行2级或3级窝重建后，由严格标准定义的手术结果。我们旨在确定影响2级或3级眼窝挛缩患者使用OMG进行眼窝重建手术结果的因素。
方法：对2007年1月至2017年12月间37例自体OMG槽式重建术患者进行回顾性分析。成功的结果被定义为在没有移位的情况下佩戴眼睛假体，并且在接受腔重建后没有任何重新手术或其他手术。使用多变量分析确定影响手术结果的因素。
结果：共纳入15例男性和22例女性患者（平均年龄：40.2±17.2岁）。窝挛缩的中位持续时间为21.5年。2级和3级窝挛缩，根据陶菲克的分类，在20和17名患者中报告，分别。28例和8例患者单独使用OMG和OMG联合硬腭移植物进行了窝重建，分别。2、3级腔窝挛缩重建成功率分别为80.0%和52.9%,分别。多变量分析表明，只有3级挛缩是预后较差的预测因素。在最后一次访问（平均随访：6.3年），34名患者（91.9％）可以佩戴眼睛假体。
结论：使用自体OMG进行Socket重建可以在2级和3级挛缩中提供可接受的结果；但是，2级患者的满意结果比3级患者的满意结果更为显著.
方法：对2007年1月至2017年12月间37例自体OMG槽式重建术患者进行回顾性分析。成功的结果被定义为在没有移位的情况下佩戴眼睛假体，并且在接受腔重建后没有任何重新手术或其他手术。使用多变量分析确定影响手术结果的因素。
结果：共纳入15例男性和22例女性患者（平均年龄：40.2±17.2岁）。窝挛缩的中位持续时间为21.5年。2级和3级窝挛缩，根据陶菲克的分类，在20和17名患者中报告，分别。28例和8例患者单独使用OMG和OMG联合硬腭移植物进行了窝重建，分别。2、3级腔窝挛缩重建成功率分别为80.0%和52.9%,分别。多变量分析表明，只有3级挛缩是预后较差的预测因素。在最后一次访问（平均随访：6.3年），34名患者（91.9％）可以佩戴眼睛假体。
结论：使用自体OMG进行Socket重建可以在2级和3级挛缩中提供可接受的结果；但是，2级患者的满意结果比3级患者的满意结果更为显著.
