关键词: Glioma Hand motor cortex Hemisphere Magnetic resonance imaging Morphological study

来  源:   DOI:10.1016/j.heliyon.2024.e28548   PDF(Pubmed)

Abstract:
UNASSIGNED: The hand motor cortex (HMC) is a reliable anatomical landmark for identifying the precentral gyrus. The current study aimed to investigate the morphology of HMC on axial MRI of glioma patients, propose a new morphological classification of HMC and analyze the effect of tumors on the morphology of HMC.
UNASSIGNED: A retrospective study of 276 adult right-handed glioma patients was conducted. The morphology of HMC was assessed using T2 axial images. Subsequently, the distribution of morphological subtypes was compared between the bilateral hemispheres and the tumor-affected and healthy hemispheres. Finally, the influence of tumor pathology on the morphology of HMC was investigated.
UNASSIGNED: A new morphological classification of HMC with four subtypes (Ω, ε, Ω-ε and ε-Ω) was proposed. No significant difference was identified in the distribution of morphological subtypes between the bilateral hemispheres (p = 0.0901, Chi-square test), or between the tumor-affected and healthy hemispheres (p = 0.3507, Chi-square test), and the morphology of HMC between the bilateral hemispheres were consistent (p < 0.0001, Kappa test). In addition, a significant difference was identified in the distribution of morphological subtypes between astrocytic and oligodendroglial tumors (p = 0.0135, Chi-square test).
UNASSIGNED: In the current study, we proposed a new morphological classification of HMC, and found that tumor could affect the morphology of HMC in glioma patients. The results can help our clinical practice, enabling us to further understand the spatial structure of the cerebral hemispheres.
摘要:
手运动皮层(HMC)是识别中央前回的可靠解剖学标志。本研究旨在探讨脑胶质瘤患者轴位MRI的HMC形态学,提出一种新的HMC形态学分类方法,分析肿瘤对HMC形态学的影响。
对276例成人右手胶质瘤患者进行了回顾性研究。使用T2轴向图像评估HMC的形态。随后,比较了双侧半球与受肿瘤影响和健康半球的形态学亚型分布.最后,研究了肿瘤病理对HMC形态学的影响。
具有四个亚型(Ω,ε,提出了Ω-ε和ε-Ω)。双侧半球之间的形态亚型分布无显著差异(p=0.0901,卡方检验),或在受肿瘤影响的半球和健康半球之间(p=0.3507,卡方检验),两侧半球间HMC形态一致(p<0.0001,Kappa检验)。此外,星形胶质细胞肿瘤和少突胶质细胞肿瘤的形态学亚型分布存在显著差异(p=0.0135,卡方检验).
在当前的研究中,我们提出了一种新的HMC形态学分类,并发现肿瘤可影响胶质瘤患者HMC的形态。结果可以帮助我们的临床实践,使我们能够进一步了解大脑半球的空间结构。
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