Abstract：
BACKGROUND: The construction of gels from low molecular weight gelators (LMWG) has been extensively studied in the fields of bio-nanotechnology and other fields. However, the understanding gaps still prevent the prediction of LMWG from the full design of those gel systems. Gels with multicomponent become even more complicated because of the multiple interference effects coexist in the composite gel systems.
OBJECTIVE: This review emphasizes systems view on the understanding of multicomponent low molecular weight gels (MLMWGs), and summarizes recent progress on the construction of desired networks of MLMWGs, including self-sorting and co-assembly, as well as the challenges and approaches to understanding MLMWGs, with the hope that the opportunities from natural products and peptides can speed up the understanding process and close the gaps between the design and prediction of structures.
UNASSIGNED: This review is focused on three key concepts. Firstly, understanding the complicated multicomponent gels systems requires a systems perspective on MLMWGs. Secondly, several protocols can be applied to control self-sorting and co-assembly behaviors in those multicomponent gels system, including the certain complementary structures, chirality inducing and dynamic control. Thirdly, the discussion is anchored in challenges and strategies of understanding MLMWGs, and some examples are provided for the understanding of multicomponent gels constructed from small natural products and subtle designed short peptides.
OBJECTIVE: This review emphasizes systems view on the understanding of multicomponent low molecular weight gels (MLMWGs), and summarizes recent progress on the construction of desired networks of MLMWGs, including self-sorting and co-assembly, as well as the challenges and approaches to understanding MLMWGs, with the hope that the opportunities from natural products and peptides can speed up the understanding process and close the gaps between the design and prediction of structures.
UNASSIGNED: This review is focused on three key concepts. Firstly, understanding the complicated multicomponent gels systems requires a systems perspective on MLMWGs. Secondly, several protocols can be applied to control self-sorting and co-assembly behaviors in those multicomponent gels system, including the certain complementary structures, chirality inducing and dynamic control. Thirdly, the discussion is anchored in challenges and strategies of understanding MLMWGs, and some examples are provided for the understanding of multicomponent gels constructed from small natural products and subtle designed short peptides.
摘要：
背景：在生物纳米技术和其他领域中，已经广泛研究了由低分子量胶凝剂（LMWG）构建凝胶的方法。然而,理解上的差距仍然阻碍了从这些凝胶系统的完整设计中预测LMWG。由于复合凝胶系统中存在多种干扰效应，因此具有多组分的凝胶变得更加复杂。
目的：这篇综述强调了对多组分低分子量凝胶（MLMWGs）理解的系统观点，并总结了MLMWG理想网络建设的最新进展，包括自分类和共同组装，以及理解MLMWG的挑战和方法，希望来自天然产物和肽的机会可以加快理解过程，缩小结构设计和预测之间的差距。
■这篇综述集中在三个关键概念上。首先,了解复杂的多组分凝胶系统需要MLMWG的系统观点。其次,几种方案可用于控制这些多组分凝胶系统中的自分选和共组装行为，包括某些互补结构，手性诱导和动态控制。第三，讨论以理解MLMWG的挑战和策略为基础，并提供了一些例子来理解由小型天然产物和微妙设计的短肽构成的多组分凝胶。
目的：这篇综述强调了对多组分低分子量凝胶（MLMWGs）理解的系统观点，并总结了MLMWG理想网络建设的最新进展，包括自分类和共同组装，以及理解MLMWG的挑战和方法，希望来自天然产物和肽的机会可以加快理解过程，缩小结构设计和预测之间的差距。
■这篇综述集中在三个关键概念上。首先,了解复杂的多组分凝胶系统需要MLMWG的系统观点。其次,几种方案可用于控制这些多组分凝胶系统中的自分选和共组装行为，包括某些互补结构，手性诱导和动态控制。第三，讨论以理解MLMWG的挑战和策略为基础，并提供了一些例子来理解由小型天然产物和微妙设计的短肽构成的多组分凝胶。
