Abstract：
BACKGROUND: This study evaluated the efficacy of the selective personality-targeted PreVenture program in reducing cannabis and stimulant use over a 7-year period spanning adolescence and early adulthood.
METHODS: A cluster randomized controlled trial was conducted in 14 Australian schools. Schools were randomized to PreVenture, a brief personality-targeted selective intervention, comprising two 90-minute facilitator-led sessions delivered one week apart, or a control group (health education as usual). Only students who scored highly on one of four personality traits (anxiety sensitivity, negative thinking, impulsivity, sensation seeking) were included. Students completed online self-report questionnaires between 2012 and 2019: at baseline; post-intervention; 1-, 2-, 3-, 5.5- and 7-years post-baseline. Outcomes were past 6-months cannabis use, stimulant use (MDMA, methamphetamine or amphetamine) and cannabis-related harms.
RESULTS: The sample comprised 438 adolescents (Mage=13.4 years; SD=0.47) at baseline. Retention ranged from 51% to 79% over the 7-years. Compared to controls, the PreVenture group had significantly reduced odds of annual cannabis-related harms (OR=0.78, 95% CI=0.65-0.92). However, there were no significant group differences in the growth of cannabis use (OR=0.84, 95% CI=0.69-1.02) or stimulant use (OR=1.07, 95% CI=0.91-1.25) over the 7-year period.
CONCLUSIONS: PreVenture was effective in slowing the growth of cannabis-related harms over time, however owing to missing data over the 7-year trial, replication trials may be warranted to better understand the impact of the PreVenture intervention on cannabis and stimulant use among young Australians. Alternative implementation strategies, such as delivering the intervention in later adolescence and/or providing booster sessions, may be beneficial.
METHODS: A cluster randomized controlled trial was conducted in 14 Australian schools. Schools were randomized to PreVenture, a brief personality-targeted selective intervention, comprising two 90-minute facilitator-led sessions delivered one week apart, or a control group (health education as usual). Only students who scored highly on one of four personality traits (anxiety sensitivity, negative thinking, impulsivity, sensation seeking) were included. Students completed online self-report questionnaires between 2012 and 2019: at baseline; post-intervention; 1-, 2-, 3-, 5.5- and 7-years post-baseline. Outcomes were past 6-months cannabis use, stimulant use (MDMA, methamphetamine or amphetamine) and cannabis-related harms.
RESULTS: The sample comprised 438 adolescents (Mage=13.4 years; SD=0.47) at baseline. Retention ranged from 51% to 79% over the 7-years. Compared to controls, the PreVenture group had significantly reduced odds of annual cannabis-related harms (OR=0.78, 95% CI=0.65-0.92). However, there were no significant group differences in the growth of cannabis use (OR=0.84, 95% CI=0.69-1.02) or stimulant use (OR=1.07, 95% CI=0.91-1.25) over the 7-year period.
CONCLUSIONS: PreVenture was effective in slowing the growth of cannabis-related harms over time, however owing to missing data over the 7-year trial, replication trials may be warranted to better understand the impact of the PreVenture intervention on cannabis and stimulant use among young Australians. Alternative implementation strategies, such as delivering the intervention in later adolescence and/or providing booster sessions, may be beneficial.
摘要：
背景：这项研究评估了选择性人格针对性的PreVenture计划在青春期和成年早期的7年内减少大麻和兴奋剂使用的功效。
方法：一项整群随机对照试验在14所澳大利亚学校进行。学校被随机分配到PreVenture，一个简短的针对人格的选择性干预，包括两个90分钟的主持人主导的会议，相隔一周，或对照组（照常进行健康教育）。只有在四种人格特质之一(焦虑敏感性，消极思维,冲动,感觉寻求)被包括在内。学生在2012年至2019年之间完成了在线自我报告问卷：基线；干预后；1-，2-,3-,基线后5.5年和7年。结果是过去6个月的大麻使用，兴奋剂使用(MDMA，甲基苯丙胺或苯丙胺）和与大麻有关的危害。
结果：样本包括基线时的438名青少年（Mage=13.4岁；SD=0.47）。在这7年中，保留率从51%到79%不等。与对照组相比，PreVenture组每年发生大麻相关危害的几率显著降低(OR=0.78,95%CI=0.65~0.92).然而,在7年期间,大麻使用(OR=0.84,95%CI=0.69-1.02)或兴奋剂使用(OR=1.07,95%CI=0.91-1.25)的增长没有显著组间差异.
结论：随着时间的推移，PreVenture有效地减缓了大麻相关危害的增长，然而，由于缺乏7年试验的数据，为了更好地了解PreVenture干预措施对澳大利亚年轻人使用大麻和兴奋剂的影响,可能需要进行复制试验.替代实施战略，例如在青春期后期提供干预和/或提供助推器课程，可能是有益的。
方法：一项整群随机对照试验在14所澳大利亚学校进行。学校被随机分配到PreVenture，一个简短的针对人格的选择性干预，包括两个90分钟的主持人主导的会议，相隔一周，或对照组（照常进行健康教育）。只有在四种人格特质之一(焦虑敏感性，消极思维,冲动,感觉寻求)被包括在内。学生在2012年至2019年之间完成了在线自我报告问卷：基线；干预后；1-，2-,3-,基线后5.5年和7年。结果是过去6个月的大麻使用，兴奋剂使用(MDMA，甲基苯丙胺或苯丙胺）和与大麻有关的危害。
结果：样本包括基线时的438名青少年（Mage=13.4岁；SD=0.47）。在这7年中，保留率从51%到79%不等。与对照组相比，PreVenture组每年发生大麻相关危害的几率显著降低(OR=0.78,95%CI=0.65~0.92).然而,在7年期间,大麻使用(OR=0.84,95%CI=0.69-1.02)或兴奋剂使用(OR=1.07,95%CI=0.91-1.25)的增长没有显著组间差异.
结论：随着时间的推移，PreVenture有效地减缓了大麻相关危害的增长，然而，由于缺乏7年试验的数据，为了更好地了解PreVenture干预措施对澳大利亚年轻人使用大麻和兴奋剂的影响,可能需要进行复制试验.替代实施战略，例如在青春期后期提供干预和/或提供助推器课程，可能是有益的。
