PDF(Pubmed)
Abstract：
Dietary supplements enriched with bioactive compounds represent a promising approach to influence physiological processes and enhance longevity and overall health. Cynara cardunculus var. scolymus serves as a functional food supplement with a high concentration of bioactive compounds, which offers various health-promoting benefits. Several chronic diseases have metabolic, genetic, or inflammatory origins, which are frequently interconnected. Pharmacological treatments, although effective, often result in undesirable side effects. In this context, preventive approaches are gaining increased attention. Recent literature indicates that the consumption of bioactive compounds in the diet can positively influence the organism\'s biological functions. Polyphenols, well-known for their health benefits, are widely recognized as valuable compounds in preventing/combating various pathologies related to lifestyle, metabolism, and aging. The C. scolymus belonging to the Asteraceae family, is widely used in the food and herbal medicine fields for its beneficial properties. Although the inflorescences (capitula) of the artichoke are used for food and culinary purposes, preparations based on artichoke leaves can be used as an active ingredient in herbal medicines. Cynara scolymus shows potential benefits in different domains. Its nutritional value and health benefits make it a promising candidate for improving overall well-being. C. scolymus exhibits anti-inflammatory, antioxidant, liver-protective, bile-expelling, antimicrobial, and lipid-lowering neuroprotective properties. Different studies demonstrate that oxidative stress is the leading cause of the onset and progression of major human health disorders such as cardiovascular, neurological, metabolic, and cancer diseases. The large amount of polyphenol found in C. scolymus has an antioxidant activity, enabling it to neutralize free radicals, preventing cellular damage. This reduces the subsequent risk of developing conditions such as cancer, diabetes, and cardiovascular diseases. Additionally, these polyphenols demonstrate anti-inflammatory activity, which is closely associated with their antioxidant properties. As a result, C. scolymus has the potential to contribute to the treatment of chronic diseases, including intestinal disorders, cardiovascular diseases, and neurodegenerative pathologies. The current review discussed the nutritional profiles, potential benefits, and pharmacological effects of C. scolymus.
摘要：
富含生物活性化合物的膳食补充剂代表了影响生理过程并增强寿命和整体健康的有希望的方法。CynaraCardunculusvar.scolymus作为具有高浓度生物活性化合物的功能性食品补充剂，提供各种促进健康的好处。几种慢性疾病有代谢性，遗传,或者炎症起源，它们经常相互联系。药物治疗,虽然有效,通常会导致不良的副作用。在这种情况下，预防措施越来越受到重视。最近的文献表明，饮食中生物活性化合物的消耗可以积极影响生物体的生物学功能。多酚,以其健康益处而闻名，被广泛认为是预防/对抗与生活方式相关的各种病理的有价值的化合物，新陈代谢，和衰老。属于菊科的C.scolymus，因其有益特性而广泛用于食品和草药领域。尽管朝鲜蓟的花序（头状）用于食物和烹饪目的，基于朝鲜蓟叶的制剂可以用作草药的活性成分。Cynarascolinmus在不同领域显示出潜在的益处。它的营养价值和健康益处使其成为改善整体健康状况的有希望的候选人。C.scolymus表现出抗炎，抗氧化剂，肝脏保护，胆汁排出,抗菌，和降脂神经保护特性。不同的研究表明，氧化应激是主要的人类健康疾病如心血管疾病的发生和进展的主要原因，神经学,新陈代谢，和癌症疾病。C.scolymus中发现的大量多酚具有抗氧化活性，使它能够中和自由基，防止细胞损伤。这降低了随后发生癌症等疾病的风险，糖尿病,和心血管疾病。此外,这些多酚表现出抗炎活性，这与它们的抗氧化性能密切相关。因此,C.scolymus有可能有助于慢性疾病的治疗，包括肠道疾病，心血管疾病,和神经退行性病变。当前的审查讨论了营养概况，潜在的好处,和C.scolymus的药理作用。
