Abstract：
We report a case of acute methanol toxicity with unique optical coherence tomography findings. A 56-year-old man was referred to our ophthalmology clinic with a history of handmade vodka consumption and vision loss. On ophthalmologic examination, his vision was 20/100 in his right eye and 20/200 in his left eye. Bilateral mild optic disk hyperemia was detected on fundus examination. Because of the severity of systemic symptoms in such cases, it is very difficult to include optical coherence tomography in the ophthalmologic examination. However, we managed to perform optical coherence tomography and recorded shallow subretinal fluid and a prominent middle limiting membrane sign as acute retinal structural changes in the patient. The patient was treated with hemodialysis, intravenous ethanol, and sodium bicarbonate. On the fourth day of treatment, visual acuity improved to 20/20 in both eyes. In addition, the prominent middle limiting membrane sign and subretinal fluid disappeared. In this unusual case, retinal pigment epithelium damage and retinal ischemia may have contributed to the prominent middle limiting membrane and subretinal fluid, which are novel optical coherence tomography findings of methanol toxicity.
摘要：
我们报告了一例具有独特光学相干断层扫描结果的急性甲醇毒性病例。一名56岁的男子被转诊到我们的眼科诊所，有手工伏特加消费和视力丧失的历史。在眼科检查中，他的右眼视力是20/100，左眼是20/200。眼底检查发现双侧轻度视盘充血。由于这种情况下全身症状的严重程度，在眼科检查中很难包括光学相干断层扫描。然而,我们成功地进行了光学相干断层扫描,并记录了浅层视网膜下液和突出的中间限制膜征作为患者的急性视网膜结构改变.病人接受了血液透析治疗,静脉注射乙醇，还有碳酸氢钠.在治疗的第四天，双眼视力提高到20/20。此外,突出的中限制膜征和视网膜下液消失。在这种不寻常的情况下，视网膜色素上皮损伤和视网膜缺血可能导致了突出的中间限制膜和视网膜下液，这是甲醇毒性的新型光学相干断层扫描发现。
