PDF(Pubmed)
Abstract：
Despite intense and costly treatments, developmental dyslexia (DD) often persists into adulthood. Several brain skills unrelated to speech sound processing (i.e., phonology), including the spatial distribution of visual attention, are abnormal in DD and may represent possible treatment targets. This study explores the efficacy in DD of rightward prismatic adaptation (rPA), a visuomotor adaptation technique that enables visuo-attentive recalibration through shifts in the visual field induced by prismatic goggles. A digital intervention of rPA plus cognitive training was delivered weekly over 10 weeks to adolescents with DD (aged 13-17) assigned either to treatment (N = 35) or waitlist (N = 35) group. Efficacy was evaluated by repeated measures MANOVA assessing changes in working memory index (WMI), processing speed index (PSI), text reading speed, and words/pseudowords reading accuracy. rPA treatment was significantly more effective than waitlist (p ≤ 0.001; ηp2 = 0.815). WMI, PSI, and reading speed increased in the intervention group only (p ≤ 0.001, ηp2 = 0.67; p ≤ 0.001, ηp2 = 0.58; p ≤ 0.001, ηp2 = 0.29, respectively). Although modest change was detected for words and pseudowords accuracy in the waitlist group only (words: p ≤ 0.001, d = 0.17, pseudowords: p = 0.028; d = 0.27), between-group differences were non-significant. rPA-coupled cognitive training enhances cognitive and reading abilities in adolescents with DD. This innovative approach could have implications for early remedial treatment.
摘要：
尽管治疗激烈而昂贵，发展性阅读障碍（DD）通常持续到成年期。与语音处理无关的几种大脑技能(即，语音学)，包括视觉注意力的空间分布，DD异常，可能代表可能的治疗目标。本研究探讨了向右棱镜适应(rPA)在DD中的功效，一种视觉运动适应技术，可通过棱镜护目镜引起的视野变化来实现视觉注意的重新校准。在10周内，每周对DD（13-17岁）的青少年进行rPA加认知训练的数字干预，分配给治疗组（N=35）或等待组（N=35）。通过重复测量MANOVA评估工作记忆指数（WMI）的变化来评估疗效，处理速度指数(PSI)，文本阅读速度，和单词/伪词阅读准确性。rPA治疗显着优于等待名单（p≤0.001；ηp2=0.815）。WMI,PSI,仅干预组的阅读速度增加（分别为p≤0.001，ηp2=0.67；p≤0.001，ηp2=0.58；p≤0.001，ηp2=0.29）。尽管仅在等待列表组中检测到单词和伪词准确性的适度变化（单词：p≤0.001，d=0.17，伪词：p=0.028；d=0.27），组间差异无显著性.rPA耦合认知训练可增强DD青少年的认知和阅读能力。这种创新方法可能对早期补救治疗产生影响。
