PDF(Pubmed)
Abstract：
BACKGROUND: Multiple primary malignant tumors (MPMTs) are rare type of cancer, especially when solid tumors are the first and lymphoma is the second primary malignancy. We report a patient with heterochronous MPMTs consisting of prostate cancer and rectal diffuse large B-cell lymphoma (DLBCL).
METHODS: We report a 77-year-old male patient diagnosed with prostate cancer who was treated with radiation therapy and one year of endocrine therapy with bicalutamide (50 mg per day) and an extended-release implant of goserelin (1/28 d). Seven years later, rectal DLBCL with lung metastases was found.
CONCLUSIONS: Although rare, the possibility of prostate cancer combined with a double primary cancer of DLBCL can provide a deeper understanding.
METHODS: We report a 77-year-old male patient diagnosed with prostate cancer who was treated with radiation therapy and one year of endocrine therapy with bicalutamide (50 mg per day) and an extended-release implant of goserelin (1/28 d). Seven years later, rectal DLBCL with lung metastases was found.
CONCLUSIONS: Although rare, the possibility of prostate cancer combined with a double primary cancer of DLBCL can provide a deeper understanding.
摘要：
背景：多原发恶性肿瘤（MPMT）是一种罕见的癌症，特别是当实体瘤是第一和淋巴瘤是第二原发性恶性肿瘤。我们报告了一例由前列腺癌和直肠弥漫性大B细胞淋巴瘤（DLBCL）组成的非同步MPMT患者。
方法：我们报告了一名被诊断为前列腺癌的77岁男性患者，他接受了放射治疗和一年的内分泌治疗，使用比卡鲁胺（每天50mg）和戈舍瑞林缓释植入物（1/28d）。七年后,发现直肠DLBCL伴肺转移。
结论：虽然罕见，对前列腺癌合并DLBCL双原发癌的可能性有更深入的了解。
方法：我们报告了一名被诊断为前列腺癌的77岁男性患者，他接受了放射治疗和一年的内分泌治疗，使用比卡鲁胺（每天50mg）和戈舍瑞林缓释植入物（1/28d）。七年后,发现直肠DLBCL伴肺转移。
结论：虽然罕见，对前列腺癌合并DLBCL双原发癌的可能性有更深入的了解。
