{Reference Type}: Case Reports
{Title}: Heterochronous multiple primary prostate cancer and lymphoma: A case report.
{Author}: Liang JL;Bu YQ;Peng LL;Zhang HZ;
{Journal}: World J Clin Cases
{Volume}: 12
{Issue}: 7
{Year}: 2024 Mar 6
{Factor}: 1.534
{DOI}: 10.12998/wjcc.v12.i7.1333
{Abstract}: <B>BACKGROUND: </B>Multiple primary malignant tumors (MPMTs) are rare type of cancer, especially when solid tumors are the first and lymphoma is the second primary malignancy. We report a patient with heterochronous MPMTs consisting of prostate cancer and rectal diffuse large B-cell lymphoma (DLBCL).<BR><B>METHODS: </B>We report a 77-year-old male patient diagnosed with prostate cancer who was treated with radiation therapy and one year of endocrine therapy with bicalutamide (50 mg per day) and an extended-release implant of goserelin (1/28 d). Seven years later, rectal DLBCL with lung metastases was found.<BR><B>CONCLUSIONS: </B>Although rare, the possibility of prostate cancer combined with a double primary cancer of DLBCL can provide a deeper understanding.