%0 Case Reports
%T Heterochronous multiple primary prostate cancer and lymphoma: A case report.
%A Liang JL
%A Bu YQ
%A Peng LL
%A Zhang HZ
%J World J Clin Cases
%V 12
%N 7
%D 2024 Mar 6
%M 38524523
%F 1.534
%R 10.12998/wjcc.v12.i7.1333
%X <B>BACKGROUND: </B>Multiple primary malignant tumors (MPMTs) are rare type of cancer, especially when solid tumors are the first and lymphoma is the second primary malignancy. We report a patient with heterochronous MPMTs consisting of prostate cancer and rectal diffuse large B-cell lymphoma (DLBCL).<BR><B>METHODS: </B>We report a 77-year-old male patient diagnosed with prostate cancer who was treated with radiation therapy and one year of endocrine therapy with bicalutamide (50 mg per day) and an extended-release implant of goserelin (1/28 d). Seven years later, rectal DLBCL with lung metastases was found.<BR><B>CONCLUSIONS: </B>Although rare, the possibility of prostate cancer combined with a double primary cancer of DLBCL can provide a deeper understanding.