Abstract：
Intramedullary schwannoma is a relatively rare tumor with only a few literature reports. This study was aimed to report the clinical characteristics of intramedullary schwannoma and discuss imaging findings and treatment strategies.
The inclusion criterion was consecutive patients with intramedullary schwannomas who were surgically treated in our institution between 2017 and 2022. Data included clinical characteristics, radiologic features, surgical management, and prognosis. Clinical and follow-up details of all cases were collected and reviewed.
This study included 3 male and 8 female patients. The mean age was 45 years (range 26-77 years). Cervical spine (4 cases, 36.4%), thoracic spine (4 cases, 36.4%), and lumbosacral spine (3 cases, 27.3%) involvement was found. Weakness, numbness and pain of limbs were the main symptoms at administration. Preoperative magnetic resonance imaging demonstrated lesion with spinal cord medullary invasion and well demarcated margins. The postoperative histologic examination showed benign lesions and confirmed the schwannoma.
This article presented a series of 11 cases of intramedullary schwannoma with sharp margins and well-enhanced features. Prognosis and functional recovery were good after gross total resection.
The inclusion criterion was consecutive patients with intramedullary schwannomas who were surgically treated in our institution between 2017 and 2022. Data included clinical characteristics, radiologic features, surgical management, and prognosis. Clinical and follow-up details of all cases were collected and reviewed.
This study included 3 male and 8 female patients. The mean age was 45 years (range 26-77 years). Cervical spine (4 cases, 36.4%), thoracic spine (4 cases, 36.4%), and lumbosacral spine (3 cases, 27.3%) involvement was found. Weakness, numbness and pain of limbs were the main symptoms at administration. Preoperative magnetic resonance imaging demonstrated lesion with spinal cord medullary invasion and well demarcated margins. The postoperative histologic examination showed benign lesions and confirmed the schwannoma.
This article presented a series of 11 cases of intramedullary schwannoma with sharp margins and well-enhanced features. Prognosis and functional recovery were good after gross total resection.
摘要：
背景：髓内神经鞘瘤是一种相对罕见的肿瘤，只有少数文献报道。本研究旨在报道髓内神经鞘瘤的临床特征，并讨论影像学表现和治疗策略。
方法：纳入标准是2017年至2022年在我们机构接受手术治疗的连续髓内神经鞘瘤患者。数据包括临床特征，放射学特征，手术管理,和预后。收集并审查所有病例的临床和随访细节。
结果：本研究包括3名男性和8名女性患者。平均年龄为45岁（26-77岁）。颈椎（4例，36.4%），胸椎（4例，36.4%），和腰骶椎（3例，27.3%)参与。弱点,肢体麻木和疼痛是给药时的主要症状。术前磁共振成像显示病变伴脊髓髓质浸润，边缘边界清晰。术后组织学检查显示良性病变并证实神经鞘瘤。
结论：本文介绍了一系列11例髓内神经鞘瘤，具有明显的边缘和强化特征。大体全切除后预后和功能恢复良好。
方法：纳入标准是2017年至2022年在我们机构接受手术治疗的连续髓内神经鞘瘤患者。数据包括临床特征，放射学特征，手术管理,和预后。收集并审查所有病例的临床和随访细节。
结果：本研究包括3名男性和8名女性患者。平均年龄为45岁（26-77岁）。颈椎（4例，36.4%），胸椎（4例，36.4%），和腰骶椎（3例，27.3%)参与。弱点,肢体麻木和疼痛是给药时的主要症状。术前磁共振成像显示病变伴脊髓髓质浸润，边缘边界清晰。术后组织学检查显示良性病变并证实神经鞘瘤。
结论：本文介绍了一系列11例髓内神经鞘瘤，具有明显的边缘和强化特征。大体全切除后预后和功能恢复良好。
