关键词: Mycobacterium abscessus antibiotic resistance cutaneous infection plastic surgery treatment

来  源:   DOI:10.2147/CCID.S445175   PDF(Pubmed)

Abstract:
UNASSIGNED: Mycobacterium abscessus is ubiquitous in the environment and seldom causes infections in immunocompetent individuals. However, skin and soft tissue infections caused by M. abscessus have been reported in recent years. Additionally, the cutaneous infections or outbreaks post cosmetic surgery caused by M. abscessus have been increasing due to the popularity of plastic surgery. The main modes of transmission are through contaminated saline, disinfectants, or surgery equipment, as well as close contact between patients. This article describes three patients who were admitted to our hospital between November 2019 and October 2020. They presented with long-term non-healing wounds caused by M. abscessus infection after undergoing plastic surgery. Symptoms presented by the three patients included swelling, ulceration, secretion, and pain. After identification of M. abscessus with Ziehl-Neelsen staining and MALDI-TOF MS system, the patients were treated with surgical debridement and clarithromycin.
UNASSIGNED: It is important to note that a long-term wound that does not heal, especially after plastic surgery, should raise suspicion for M. abscessus infection. The infection mechanism in these three patients may have been due to exposure to surgical equipment that was not properly sterilized or due to poor sterile technique by the plastic surgeon. To prevent such infections, it is important to ensure proper sterilization of surgical equipment and saline.
摘要:
脓肿分枝杆菌在环境中普遍存在,很少在有免疫能力的个体中引起感染。然而,近年来,脓肿分枝杆菌引起的皮肤和软组织感染已有报道。此外,由于整形手术的普及,由脓肿分枝杆菌引起的整容手术后的皮肤感染或爆发一直在增加。主要的传播方式是通过受污染的盐水,消毒剂,或者手术设备,以及患者之间的密切接触。本文介绍了2019年11月至2020年10月期间入住我院的三名患者。他们在接受整形手术后出现了由脓肿分枝杆菌感染引起的长期不愈合的伤口。三名患者的症状包括肿胀,溃疡,分泌,和痛苦。用Ziehl-Neelsen染色和MALDI-TOFMS系统鉴定脓肿分枝杆菌后,患者接受手术清创术和克拉霉素治疗。
重要的是要注意无法愈合的长期伤口,尤其是整形手术后,应该怀疑脓肿分枝杆菌感染。这三名患者的感染机制可能是由于暴露于未适当消毒的手术设备或由于整形外科医生的无菌技术不佳。为了防止这种感染,重要的是确保手术设备和盐水的适当灭菌。
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