PDF(Pubmed)
Abstract：
UNASSIGNED: The term white dot syndromes has been used to refer conditions that differ in their morphology and prognosis. We report three cases of different pathologies encompassed within the white dot syndromes.
UNASSIGNED: Case 1: A 26-year-old female presented with scotoma in her right eye. Fundus examination revealed multiple white dots that demonstrated early hyperfluorescence with late staining on FA. OCT showed discontinuities in inner segment-outer segment junction associated with columnar-shaped outer retinal hyperreflective bands. AF revealed multiple hyperautofluorescent dots around the posterior pole, compatible with multiple evanescent white dot syndrome. The symptoms improved without treatment. Case 2: A 16-year-old male presented with retinal lesions compatible with punctate inner choroidopathy in his right eye. OCT showed lesion in the outer retinal layer. FAF revealed parafoveal hypoautofluorescent dots with early hyperfluorescence and late staining on FFA. After oral corticotherapy, they progress to atrophic scars. Case 3: A 65-year-old male presented with scotoma and decreased vision in his right eye. OCT showed hyperreflectivity in the outer layer that progresses to a large atrophic plaque with foveal affectation. FAF demonstrated hyperautofluorescent placoid lesion occupying macular area, compatible with acute posterior multifocal placoid pigment epitheliopathy. Retinal lesions improved with systemic corticosteroids.
UNASSIGNED: The FAF pattern helps know the distribution of the lesions. It represents a noninvasive method that has been shown to be useful in the diagnosis and monitoring of white dot syndromes.
UNASSIGNED: Case 1: A 26-year-old female presented with scotoma in her right eye. Fundus examination revealed multiple white dots that demonstrated early hyperfluorescence with late staining on FA. OCT showed discontinuities in inner segment-outer segment junction associated with columnar-shaped outer retinal hyperreflective bands. AF revealed multiple hyperautofluorescent dots around the posterior pole, compatible with multiple evanescent white dot syndrome. The symptoms improved without treatment. Case 2: A 16-year-old male presented with retinal lesions compatible with punctate inner choroidopathy in his right eye. OCT showed lesion in the outer retinal layer. FAF revealed parafoveal hypoautofluorescent dots with early hyperfluorescence and late staining on FFA. After oral corticotherapy, they progress to atrophic scars. Case 3: A 65-year-old male presented with scotoma and decreased vision in his right eye. OCT showed hyperreflectivity in the outer layer that progresses to a large atrophic plaque with foveal affectation. FAF demonstrated hyperautofluorescent placoid lesion occupying macular area, compatible with acute posterior multifocal placoid pigment epitheliopathy. Retinal lesions improved with systemic corticosteroids.
UNASSIGNED: The FAF pattern helps know the distribution of the lesions. It represents a noninvasive method that has been shown to be useful in the diagnosis and monitoring of white dot syndromes.
摘要：
■术语“白点综合征”已用于指形态学和预后不同的病症。我们报告了白点综合征中包含的三例不同病理。
■病例1：一名26岁女性右眼暗点。眼底检查显示多个白点，这些白点显示出早期的高荧光，对FA进行了后期染色。OCT显示与柱状视网膜外反射带相关的内节-外节交界处不连续。AF显示后极周围有多个高自发荧光点，与多个渐逝白点综合征相容。症状未经治疗改善。病例2：一名16岁男性，右眼出现与点状内部脉络膜病变相符的视网膜病变。OCT显示视网膜外层有病变。FAF显示副凹低自发荧光点，在FFA上具有早期的高荧光和晚期染色。口服皮质治疗后，他们进展到萎缩性疤痕。病例3：一名65岁男性出现暗点，右眼视力下降。OCT显示外层的高反射率，进展为大的萎缩性斑块，并伴有中央凹。FAF显示高自体荧光胎盘样病变占据黄斑区，与急性后部多灶性胎盘样色素上皮病变相容。全身性皮质类固醇可改善视网膜病变。
■FAF模式有助于了解病变的分布。它代表了一种非侵入性方法，已被证明可用于白点综合征的诊断和监测。
■病例1：一名26岁女性右眼暗点。眼底检查显示多个白点，这些白点显示出早期的高荧光，对FA进行了后期染色。OCT显示与柱状视网膜外反射带相关的内节-外节交界处不连续。AF显示后极周围有多个高自发荧光点，与多个渐逝白点综合征相容。症状未经治疗改善。病例2：一名16岁男性，右眼出现与点状内部脉络膜病变相符的视网膜病变。OCT显示视网膜外层有病变。FAF显示副凹低自发荧光点，在FFA上具有早期的高荧光和晚期染色。口服皮质治疗后，他们进展到萎缩性疤痕。病例3：一名65岁男性出现暗点，右眼视力下降。OCT显示外层的高反射率，进展为大的萎缩性斑块，并伴有中央凹。FAF显示高自体荧光胎盘样病变占据黄斑区，与急性后部多灶性胎盘样色素上皮病变相容。全身性皮质类固醇可改善视网膜病变。
■FAF模式有助于了解病变的分布。它代表了一种非侵入性方法，已被证明可用于白点综合征的诊断和监测。
