2019年冠状病毒病(COVID-19)大流行的出现影响了各种疾病的发病率和病程,许多研究调查了与COVID-19和相应疫苗相关的眼部受累。在这项研究中,我们在韩国的一个中心比较了COVID-19大流行前和期间多发性渐逝白点综合征(MEWDS)的发病率,并分析了COVID-19大流行期间出现MEWDS患者的人口统计学和临床特征.我们根据诊断日期将MEWDS患者分为两组。Pre-COVID19组包括在大流行前期间(2017年3月11日至2020年3月10日)诊断的患者,而COVID19组包括在大流行期间(2020年3月11日至2023年3月10日)诊断的患者.6例和12例患者被纳入前COVID19组和后COVID19组,分别。在大流行前和大流行期间的所有医院就诊中,0.011%和0.030%是由于MEWDS,表明在大流行期间显着增加(p=0.029,B=2.756)。2017-2022年MEWDS患者年发病率分别为0.73、0.75、0.78、1.32、2.49和2.07/10,分别,对应于显著增加(p=0.039,B=1.316)。我们的结果表明,在COVID-19大流行时代,MEWDS的发病率和表现可能变得更加多样化。
The advent of coronavirus disease 2019 (COVID-19) pandemic has affected the incidence and course of various diseases and numerous studies have investigated ocular involvement associated with COVID-19 and corresponding vaccines. In this study, we compared the incidence of multiple evanescent white dot syndrome (MEWDS) before and during the COVID-19 pandemic at a single center in Korea and analyzed the demographic and clinical features of patients with MEWDS presenting during the COVID-19 pandemic. We categorized patients with MEWDS into two groups according to date of diagnosis. Pre-COVID19 group included patients diagnosed during the pre-pandemic period (between March 11, 2017, and March 10, 2020), whereas post-COVID19 group included patients diagnosed during the pandemic period (between March 11, 2020, and March 10, 2023). 6 and 12 patients were included in pre-COVID19 group and post-COVID19 group, respectively. Among all hospital visits during the pre-pandemic and pandemic periods, 0.011% and 0.030% were due to MEWDS, indicating a significant increase during the pandemic (p = 0.029, B = 2.756). The annual incidence of patients with MEWDS in 2017-2022 were 0.73, 0.75, 0.78, 1.32, 2.49, and 2.07 per 10,000 population, respectively, corresponding to a significant increase (p = 0.039, B = 1.316). Our results imply that the incidence and manifestation of MEWDS are likely to become more diverse in the COVID-19 pandemic era.