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Abstract：
OBJECTIVE: To analyze structural changes in the macular retinal layers and sub-foveal choroidal thickness (SFCT) in eyes after macula-on rhegmatogenous retinal detachment (RRD) repair by pars plana vitrectomy with either silicone oil (SO) or gas tamponade, and the effect of these changes on visual acuity.
METHODS: Retrospective study which included 26 eyes in the SO Group and 32 in the Gas Group. Optical coherence tomography (OCT) scans of the affected eyes were obtained before surgery, and 3 months after PPV in the Gas Group, and during silicone oil in situ and 3 months after SO removal, in the SO Group. Qualitative assessment of photoreceptor layer and foveal contour, along with quantitative assessment of macular retinal thickness and SFCT was performed. Postoperative OCT macular microstructural changes were recorded and correlated to corrected distance visual acuity (CDVA). Intraocular pressure (IOP) was measured preoperative and at 3 months post operative.
RESULTS: There was a 2-line loss (from 20/28 preoperatively to 20/40 at final follow-up) of CDVA in the SO Group (p=0.051), while there was no statistically significant change in CDVA in the Gas Group (p=0.786). There was no significant correlation between CDVA loss and duration of silicon tamponade (r=-0.031, p=0.893). There was a statistically significant increase in IOP from its baseline to final follow-up of 0.7 mmHg in the SO Group (p=0.023) while there was no statistically significant change in IOP in the Gas Group. During silicone oil tamponade, there was approximately 11% and 5% of retinal and sub-foveal choroidal thinning respectively, which was moderately resolved following silicone oil removal. 20% (5/24) of eyes in the SO Group had qualitative flattening of foveal contour during SO tamponade that resolved after SO removal.
CONCLUSIONS: Thinning of the macula was noticed after macula-on RRD repair with SO tamponade. Such thinning was only partially reversible after the removal of SO.
METHODS: Retrospective study which included 26 eyes in the SO Group and 32 in the Gas Group. Optical coherence tomography (OCT) scans of the affected eyes were obtained before surgery, and 3 months after PPV in the Gas Group, and during silicone oil in situ and 3 months after SO removal, in the SO Group. Qualitative assessment of photoreceptor layer and foveal contour, along with quantitative assessment of macular retinal thickness and SFCT was performed. Postoperative OCT macular microstructural changes were recorded and correlated to corrected distance visual acuity (CDVA). Intraocular pressure (IOP) was measured preoperative and at 3 months post operative.
RESULTS: There was a 2-line loss (from 20/28 preoperatively to 20/40 at final follow-up) of CDVA in the SO Group (p=0.051), while there was no statistically significant change in CDVA in the Gas Group (p=0.786). There was no significant correlation between CDVA loss and duration of silicon tamponade (r=-0.031, p=0.893). There was a statistically significant increase in IOP from its baseline to final follow-up of 0.7 mmHg in the SO Group (p=0.023) while there was no statistically significant change in IOP in the Gas Group. During silicone oil tamponade, there was approximately 11% and 5% of retinal and sub-foveal choroidal thinning respectively, which was moderately resolved following silicone oil removal. 20% (5/24) of eyes in the SO Group had qualitative flattening of foveal contour during SO tamponade that resolved after SO removal.
CONCLUSIONS: Thinning of the macula was noticed after macula-on RRD repair with SO tamponade. Such thinning was only partially reversible after the removal of SO.
摘要：
目的：分析黄斑孔源性视网膜脱离（RRD）修复后黄斑视网膜层的结构变化和中央凹下脉络膜厚度（SFCT）通过玻璃体切除术用硅油（SO）或气体填塞，以及这些变化对视力的影响。
方法：回顾性研究，包括SO组26只眼和气体组32只眼。手术前获得受累眼睛的光学相干断层扫描（OCT）扫描，在天然气集团进行PPV后3个月，在硅油原位和SO去除后3个月，在SO组。感光层和中央凹轮廓的定性评估，同时对黄斑视网膜厚度和SFCT进行定量评估.记录术后OCT黄斑微观结构变化，并与矫正视力（CDVA）相关。术前和术后3个月测量眼压（IOP）。
结果：SO组CDVA2线丢失（从术前20/28到最终随访时20/40）（p=0.051），而Gas组CDVA无统计学显著变化(p=0.786)。CDVA损失与硅填塞持续时间之间没有显着相关性（r=-0.031，p=0.893）。从基线到最终随访0.7mmHg，SO组的IOP有统计学上的显着增加（p=0.023），而气体组的IOP没有统计学上的显着变化。在硅油填塞期间，视网膜和中央凹下脉络膜变薄分别约为11%和5%，这是适度解决后硅油去除。SO组中20％（5/24）的眼睛在SO填塞过程中中央凹轮廓定性变平，在去除SO后消失。
结论：用SO填塞对RRD进行黄斑修复后，发现黄斑变薄。去除SO后，这种变薄仅是部分可逆的。
方法：回顾性研究，包括SO组26只眼和气体组32只眼。手术前获得受累眼睛的光学相干断层扫描（OCT）扫描，在天然气集团进行PPV后3个月，在硅油原位和SO去除后3个月，在SO组。感光层和中央凹轮廓的定性评估，同时对黄斑视网膜厚度和SFCT进行定量评估.记录术后OCT黄斑微观结构变化，并与矫正视力（CDVA）相关。术前和术后3个月测量眼压（IOP）。
结果：SO组CDVA2线丢失（从术前20/28到最终随访时20/40）（p=0.051），而Gas组CDVA无统计学显著变化(p=0.786)。CDVA损失与硅填塞持续时间之间没有显着相关性（r=-0.031，p=0.893）。从基线到最终随访0.7mmHg，SO组的IOP有统计学上的显着增加（p=0.023），而气体组的IOP没有统计学上的显着变化。在硅油填塞期间，视网膜和中央凹下脉络膜变薄分别约为11%和5%，这是适度解决后硅油去除。SO组中20％（5/24）的眼睛在SO填塞过程中中央凹轮廓定性变平，在去除SO后消失。
结论：用SO填塞对RRD进行黄斑修复后，发现黄斑变薄。去除SO后，这种变薄仅是部分可逆的。
