PDF(Pubmed)
Abstract：
UNASSIGNED: The study aimed to evaluate the effect of mydriasis on macular and peripapillary metrics with swept-source optical coherence tomography angiography (SS-OCTA) in healthy subjects.
UNASSIGNED: Thirty-five healthy subjects were included. The macular region was scanned by the 3×3mm mode and 6×6mm mode, and the peripapillary region was scanned by the 4.5×4.5mm mode on both eyes with SS-OCTA before and after mydriasis. Macular and peripapillary metrics, including retinal vessel density (VD) and fundus thickness were measured by the built-in program. Data of the right eye were analyzed.
UNASSIGNED: The signal strength of the scans was comparable before and after mydriasis (all P>0.05). There were no significant differences in foveal avascular zone (FAZ) parameters and retinal VD of most sectors in both macular and peripapillary areas (all P>0.05). Choroidal thickness was decreased, outer and whole retinal thickness was increased in most of the macular sectors after mydriasis (all P<0.05). Choroidal thickness was decreased in all the peripapillary sectors, but whole retinal thickness and GCC thickness were increased in some peripapillary sectors after mydriasis (all P<0.05).
UNASSIGNED: FAZ parameters and retinal VD in the most macular and peripapillary regions are not affected by mydriasis. The thickness of the choroid is decreased after mydriasis, while the thickness of retinal layers in some sectors may be increased after mydriasis.
UNASSIGNED: Thirty-five healthy subjects were included. The macular region was scanned by the 3×3mm mode and 6×6mm mode, and the peripapillary region was scanned by the 4.5×4.5mm mode on both eyes with SS-OCTA before and after mydriasis. Macular and peripapillary metrics, including retinal vessel density (VD) and fundus thickness were measured by the built-in program. Data of the right eye were analyzed.
UNASSIGNED: The signal strength of the scans was comparable before and after mydriasis (all P>0.05). There were no significant differences in foveal avascular zone (FAZ) parameters and retinal VD of most sectors in both macular and peripapillary areas (all P>0.05). Choroidal thickness was decreased, outer and whole retinal thickness was increased in most of the macular sectors after mydriasis (all P<0.05). Choroidal thickness was decreased in all the peripapillary sectors, but whole retinal thickness and GCC thickness were increased in some peripapillary sectors after mydriasis (all P<0.05).
UNASSIGNED: FAZ parameters and retinal VD in the most macular and peripapillary regions are not affected by mydriasis. The thickness of the choroid is decreased after mydriasis, while the thickness of retinal layers in some sectors may be increased after mydriasis.
摘要：
■该研究旨在通过扫频源光学相干断层扫描血管造影（SS-OCTA）评估散瞳对健康受试者黄斑和乳头周围指标的影响。
■包括35名健康受试者。以3×3mm模式和6×6mm模式扫描黄斑区，散瞳前后用SS-OCTA对双眼进行4.5×4.5mm模式扫描。黄斑和乳头周围指标，包括视网膜血管密度（VD）和眼底厚度通过内置程序进行测量。分析右眼的数据。
■散瞳前后扫描的信号强度相当（均P>0.05）。黄斑区和乳头周围区大部分部位的中央凹无血管区（FAZ）参数和视网膜VD差异均无统计学意义（均P>0.05）。脉络膜厚度减少，散瞳后大部分黄斑区的外部和整个视网膜厚度增加（均P<0.05）。脉络膜厚度在所有的乳头周围部分都减少了，但散瞳后部分乳头周围部分视网膜整体厚度和GCC厚度增加（均P<0.05）。
■大多数黄斑和乳头周围区域的FAZ参数和视网膜VD不受散瞳的影响。散瞳后脉络膜厚度减少，而散瞳后，某些部门的视网膜层厚度可能会增加。
■包括35名健康受试者。以3×3mm模式和6×6mm模式扫描黄斑区，散瞳前后用SS-OCTA对双眼进行4.5×4.5mm模式扫描。黄斑和乳头周围指标，包括视网膜血管密度（VD）和眼底厚度通过内置程序进行测量。分析右眼的数据。
■散瞳前后扫描的信号强度相当（均P>0.05）。黄斑区和乳头周围区大部分部位的中央凹无血管区（FAZ）参数和视网膜VD差异均无统计学意义（均P>0.05）。脉络膜厚度减少，散瞳后大部分黄斑区的外部和整个视网膜厚度增加（均P<0.05）。脉络膜厚度在所有的乳头周围部分都减少了，但散瞳后部分乳头周围部分视网膜整体厚度和GCC厚度增加（均P<0.05）。
■大多数黄斑和乳头周围区域的FAZ参数和视网膜VD不受散瞳的影响。散瞳后脉络膜厚度减少，而散瞳后，某些部门的视网膜层厚度可能会增加。
