关键词: Haematology (incl blood transfusion) Pleural infection Respiratory medicine Travel medicine Tropical medicine (infectious disease)

Mesh : Humans Female Leishmaniasis, Visceral / complications diagnosis drug therapy Pleural Effusion / diagnostic imaging etiology pathology Exudates and Transudates Bone Marrow / pathology

来  源:   DOI:10.1136/bcr-2023-256632   PDF(Pubmed)

Abstract:
We present a rare case of recurrent leishmaniasis infection in a female in her 80s who re-presented with a pleural effusion. The patient was initially investigated as an outpatient for cytopenia and underwent a bone marrow biopsy which subsequently diagnosed visceral leishmaniasis. Following full treatment, and apparent recovery, she re-presented with pleural effusion, hypoalbuminaemia and cytopenia. Leishmania was eventually isolated in a pleural fluid sample obtained on therapeutic drainage, and she was treated for a recurrence at a tertiary infectious disease unit. This interesting and challenging case demonstrates the importance of suspecting leishmaniasis recurrence in previously treated cases and the diagnostic benefit of pleural fluid analysis in the context of suspected leishmaniasis.
摘要:
我们介绍了一名80多岁的女性复发性利什曼病感染的罕见病例,该女性再次出现胸腔积液。该患者最初是作为血细胞减少症的门诊患者进行调查,并接受了骨髓活检,随后诊断为内脏利什曼病。经过全面治疗,和明显的恢复,她又出现了胸腔积液,低蛋白血症和血细胞减少。利什曼原虫最终从治疗性引流获得的胸膜液样本中分离出来,她在三级传染病科接受了复发治疗。这个有趣且具有挑战性的案例证明了在先前治疗的病例中怀疑利什曼病复发的重要性,以及在怀疑利什曼病的情况下,胸腔积液分析的诊断益处。
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