PDF(Pubmed)
Abstract：
BACKGROUND: In the application of APTw protocols for evaluating tumors and parotid glands, inhomogeneity and hyperintensity artifacts have remained an obstacle. This study aimed to improve APTw imaging quality and evaluate the feasibility of difference B1 values to detect parotid tumors.
METHODS: A total of 31 patients received three APTw sequences to acquire 32 lesions and 30 parotid glands (one patient had lesions on both sides). Patients received T2WI and 3D turbo-spin-echo (TSE) APTw imaging on a 3.0 T scanner for three sequences (B1 = 2 μT, 1 μT, and 0.7 μT in APTw 1, 2, and 3, respectively). APTw image quality was evaluated using four-point Likert scales in terms of integrity and hyperintensity artifacts. Image quality was compared between the three sequences. An evaluable group and a trustable group were obtained for APTmean value comparison.
RESULTS: Tumors in both APT2 and APT3 had fewer hyperintensity artifacts than in APT1. With B1 values decreasing, tumors had less integrity in APTw imaging. APTmean values of tumors were higher than parotid glands in traditional APT1 sequence though not significant, while the APTmean subtraction value was significantly different.
CONCLUSIONS: Applying a lower B1 value could remove hyperintensity but could also compromise its integrity. Combing different APTw sequences might increase the feasibility of tumor detection.
METHODS: A total of 31 patients received three APTw sequences to acquire 32 lesions and 30 parotid glands (one patient had lesions on both sides). Patients received T2WI and 3D turbo-spin-echo (TSE) APTw imaging on a 3.0 T scanner for three sequences (B1 = 2 μT, 1 μT, and 0.7 μT in APTw 1, 2, and 3, respectively). APTw image quality was evaluated using four-point Likert scales in terms of integrity and hyperintensity artifacts. Image quality was compared between the three sequences. An evaluable group and a trustable group were obtained for APTmean value comparison.
RESULTS: Tumors in both APT2 and APT3 had fewer hyperintensity artifacts than in APT1. With B1 values decreasing, tumors had less integrity in APTw imaging. APTmean values of tumors were higher than parotid glands in traditional APT1 sequence though not significant, while the APTmean subtraction value was significantly different.
CONCLUSIONS: Applying a lower B1 value could remove hyperintensity but could also compromise its integrity. Combing different APTw sequences might increase the feasibility of tumor detection.
摘要：
背景：在应用APTw方案评估肿瘤和腮腺时，不均匀性和高强度伪影仍然是一个障碍。本研究旨在提高APTw成像质量,评价差异B1值检测腮腺肿瘤的可行性。
方法：共有31例患者接受了三个APTw序列，获得了32个病变和30个腮腺（一名患者两侧均有病变）。患者在3.0T扫描仪上接受T2WI和3D涡轮自旋回波（TSE）APTw成像三个序列（B1=2μT，1μT,和APTw1、2和3中的0.7μT)。在完整性和高强度伪影方面，使用四点Likert量表评估了APTw图像质量。在三个序列之间比较图像质量。获得可评估组和可信任组进行APT平均值比较。
结果：与APT1相比，APT2和APT3中的肿瘤具有更少的高强度伪影。随着B1值的减小，在APTw成像中,肿瘤的完整性较低.传统APT1序列中肿瘤的APT均值高于腮腺,而APTmean减法值有显著差异。
结论：应用较低的B1值可以消除高强度，但也可能损害其完整性。结合不同的APTw序列可能会增加肿瘤检测的可行性。
方法：共有31例患者接受了三个APTw序列，获得了32个病变和30个腮腺（一名患者两侧均有病变）。患者在3.0T扫描仪上接受T2WI和3D涡轮自旋回波（TSE）APTw成像三个序列（B1=2μT，1μT,和APTw1、2和3中的0.7μT)。在完整性和高强度伪影方面，使用四点Likert量表评估了APTw图像质量。在三个序列之间比较图像质量。获得可评估组和可信任组进行APT平均值比较。
结果：与APT1相比，APT2和APT3中的肿瘤具有更少的高强度伪影。随着B1值的减小，在APTw成像中,肿瘤的完整性较低.传统APT1序列中肿瘤的APT均值高于腮腺,而APTmean减法值有显著差异。
结论：应用较低的B1值可以消除高强度，但也可能损害其完整性。结合不同的APTw序列可能会增加肿瘤检测的可行性。
