关键词: Complexity Differentiation Dynamics Fractal Fractal time space Gompertz growth Neurons Persistent homology Synapse

Mesh : Humans Fractals Nonlinear Dynamics Neurons / physiology

来  源:   DOI:10.1007/978-3-031-47606-8_9

Abstract:
Synapse formation is a unique biological phenomenon. The molecular biological perspective of this phenomenon is different from the fractal geometrical one. However, these perspectives are not mutually exclusive and supplement each other. The cornerstone of the first one is a chain of biochemical reactions with the Markov property, that is, a deterministic, conditional, memoryless process ordered in time and in space, in which the consecutive stages are determined by the expression of some regulatory proteins. The coordination of molecular and cellular events leading to synapse formation occurs in fractal time space, that is, the space that is not only the arena of events but also actively influences those events. This time space emerges owing to coupling of time and space through nonlinear dynamics. The process of synapse formation possesses fractal dynamics with non-Gaussian distribution of probability and a reduced number of molecular Markov chains ready for transfer of biologically relevant information.
摘要:
突触形成是一种独特的生物学现象。这种现象的分子生物学观点不同于分形几何。然而,这些观点并不是相互排斥和相辅相成的。第一个的基石是具有马尔可夫性质的生化反应链,也就是说,一个确定性的,有条件的,在时间和空间上有序的无记忆过程,其中连续阶段由一些调节蛋白的表达决定。导致突触形成的分子和细胞事件的协调发生在分形时空,也就是说,空间不仅是事件的舞台,而且还积极影响这些事件。由于时间和空间通过非线性动力学耦合,因此出现了该时间空间。突触形成的过程具有分形动力学,具有非高斯分布的概率和减少数量的分子马尔可夫链,可用于传递生物相关信息。
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