PDF(Pubmed)
Abstract：
Tuber plants are of great significance in the world as human food crops. Polysaccharides, important metabolites in tuber plants, also serve as a source of innovative drugs with significant pharmacological effects. These drugs are particularly known for their immunomodulation and antitumor properties. To fully exploit the potential value of tuber plant polysaccharides and establish a synthetic system for their targeted synthesis, it is crucial to dissect their metabolic processes and genetic regulatory mechanisms. In this article, we provide a comprehensive summary of the basic pathways involved in the synthesis of various types of tuber plant polysaccharides. We also outline the key research progress that has been made in this area in recent years. We classify the main types and functions of tuber plant polysaccharides and analyze the biosynthetic processes and genetic regulation mechanisms of key enzymes involved in the metabolic pathways of starch, cellulose, pectin, and fructan in tuber plants. We have identified hexokinase and glycosyltransferase as the key enzymes involved in the polysaccharide synthesis process. By elucidating the synthesis pathway of polysaccharides in tuber plants and understanding the underlying mechanism of action of key enzymes in the metabolic pathway, we can provide a theoretical framework for enhancing the yield of polysaccharides and other metabolites in plant culture cells. This will ultimately lead to increased production efficiency.
摘要：
块茎植物作为人类食粮作物在世界上具有主要意义。多糖，块茎植物中的重要代谢产物，也可以作为具有显着药理作用的创新药物的来源。这些药物因其免疫调节和抗肿瘤特性而特别为人所知。充分挖掘块茎植物多糖的潜在价值,建立其靶向合成的合成体系,解剖它们的代谢过程和遗传调控机制至关重要。在这篇文章中,我们全面总结了各种块茎植物多糖合成的基本途径。我们还概述了近年来在该领域取得的关键研究进展。我们对块茎植物多糖的主要类型和功能进行了分类，并分析了参与淀粉代谢途径的关键酶的生物合成过程和遗传调控机制。纤维素,果胶,块茎植物中的果聚糖。我们已经确定己糖激酶和糖基转移酶是参与多糖合成过程的关键酶。通过阐明块茎植物中多糖的合成途径，并了解代谢途径中关键酶的潜在作用机制，我们可以为提高植物培养细胞中多糖和其他代谢产物的产量提供理论框架。这将最终提高生产效率。
