METHODS: This retrospective observational study was conducted from January 2016 to September 2022. It included 83 patients with microbiologically proven Demodex BKC who presented to the cornea department of our tertiary care eye center. The clinical, microbiological, and demographic data of the 83 cases were analyzed.
RESULTS: Of the 83 cases, 57 (68.67%) were younger than 40 years, and 25 (30.12%) were below 20. Most patients presented with a good visual acuity of 20/40 or better (93 eyes; 84.55%). The disease was unilateral in 55 patients and bilateral in 28. Cylindrical dandruff was the predominant presentation noted in 61 eyes (54.95%), followed by corneal scarring in 47 eyes (42.34%) and corneal vascularization in 40 eyes (36.04%). On light microscopy, 87.95% of the positive samples were identified as Demodex folliculorum , 7.23% as Demodex brevis , and 6.02% remained unidentified. Tea tree oil and lid scrubs eradicated the disease in most patients clinically (75/83, 90.36%).
CONCLUSIONS: The spectrum of BKC includes both lid signs and corneal involvement. It can be a cause of recurrent BKC and detection of the mite by microscopic evaluation of the lashes can confirm the diagnosis. In most cases, the tea tree oil can effectively manage this condition. However, low doses of topical steroids are needed to control the inflammation in patients with corneal involvement.
方法:这项回顾性观察研究于2016年1月至2022年9月进行。其中包括83名经过微生物验证的蠕形螨BKC患者,他们被送往我们三级护理眼科中心的角膜科。临床,微生物,并对83例患者的人口学资料进行分析。
结果:在83例中,57岁(68.67%)年龄小于40岁,25(30.12%)低于20。大多数患者的良好视力为20/40或更好(93眼;84.55%)。该疾病在55例患者中为单侧,在28例中为双侧。61只眼(54.95%)主要表现为圆柱形头皮屑,其次是角膜瘢痕47眼(42.34%)和角膜血管形成40眼(36.04%)。在光学显微镜下,87.95%的阳性样本被鉴定为毛囊蠕形螨,7.23%为蠕形螨,和6.02%仍未确认。茶树油和眼睑磨砂在临床上根除了大多数患者的疾病(75/83,90.36%)。
结论:BKC包括眼睑体征和角膜受累。它可能是BKC复发的原因,通过对睫毛的显微镜评估可以确定螨的诊断。在大多数情况下,茶树油可以有效地控制这种情况。然而,对于角膜受累患者,需要使用低剂量的局部类固醇来控制炎症.