METHODS: Elderly patients undergoing laparoscopic radical resection of colorectal cancer were randomized to receive either PPV guided GDFT or conventional fluid therapy and explore whether PPV guided GDFT can optimize the short-term prognosis of elderly patients undergoing laparoscopic radical resection of colorectal cancer compared with conventional fluid therapy.
RESULTS: The incidence of complications was significantly lower in the PPV group compared to the control group (32.8% vs. 57.1%, P = .009). Additionally, the PPV group had a lower occurrence of gastrointestinal dysfunction (19.0% vs. 39.3%, P = .017) and postoperative pneumonia (8.6% vs. 23.2%, P = .033) than the control group.
CONCLUSIONS: Utilizing PPV as a monitoring index for GDFT can improve short-term prognosis in elderly patients undergoing laparoscopic radical resection of colorectal cancer.
BACKGROUND: ChiCTR2300067361; date of registration: January 5, 2023.
方法:将接受腹腔镜结直肠癌根治术的老年患者随机分为PPV引导下的GDFT或常规液体治疗,并探讨与常规液体治疗相比,PPV引导下的GDFT是否能优化接受腹腔镜结直肠癌根治术的老年患者的短期预后。
结果:与对照组相比,PPV组的并发症发生率显着降低(32.8%vs.57.1%,P=.009)。此外,PPV组胃肠功能障碍发生率较低(19.0%vs.39.3%,P=0.017)和术后肺炎(8.6%vs.23.2%,P=0.033)比对照组。
结论:采用PPV作为GDFT的监测指标可改善老年患者腹腔镜结直肠癌根治术的近期预后。
背景:ChiCTR2300067361;注册日期:2023年1月5日。