Abstract：
Staphylococcus haemolyticus, a key species of the Staphylococcus genus, holds significant importance in healthcare-associated infections, due to its notable resistance to antimicrobials, like methicillin, and proficient biofilms-forming capabilities. This coagulase-negative bacterium poses a substantial challenge in the battle against nosocomial infections. Recent research has shed light on Staph. haemolyticus genomic plasticity, unveiling genetic elements responsible for antibiotic resistance and their widespread dissemination within the genus. This review presents an updated and comprehensive overview of the clinical significance and prevalence of Staph. haemolyticus, underscores its zoonotic potential and relevance in the one health framework, explores crucial virulence factors, and examines genetics features contributing to its success in causing emergent and challenging infections. Additionally, we scrutinize ongoing studies aimed at controlling spread and alternative approaches for combating it.
摘要：
溶血葡萄球菌，葡萄球菌属的关键物种，在医疗保健相关感染中具有重要意义，由于其对抗菌药物的显著耐药性，比如甲氧西林,和熟练的生物膜形成能力。这种凝固酶阴性细菌在与医院感染的斗争中提出了重大挑战。最近的研究揭示了葡萄球菌。溶血病基因组可塑性，揭示了负责抗生素抗性的遗传元件及其在属中的广泛传播。这篇综述对葡萄球菌的临床意义和患病率进行了更新和全面的概述。溶血病,强调了它在一个健康框架中的人畜共患潜力和相关性，探索关键的毒力因子，并检查遗传学特征有助于其成功引起紧急和具有挑战性的感染。此外,我们仔细检查正在进行的旨在控制传播的研究和打击传播的替代方法。
