Abstract：
Polycyclic aromatic hydrocarbons (PAHs), known for their health risks, are prevalent in the environment, with the coking industry being a major source of their emissions. To bridge the knowledge gap concerning the relationship between environmental and dietary PAH exposure, we explore this complex interplay by investigating the dietary exposure characteristics of 24 PAHs within a typical Chinese coking plant and their association with environmental pollution. Our research revealed Nap and Fle as primary dietary contaminants, emphasizing the significant influence of soil and atmospheric pollution on PAH exposure. We subjected our data to non-metric multidimensional scaling (NMDS), Spearman correlation analysis, Lasso regression, and Weighted Quantile Sum (WQS) regression to delve into this multifaceted phenomenon. NMDS reveals that dietary PAH exposure, especially within the high molecular weight (HMW) group, is common both within and around the coking plant. This suggests that meals prepared within the plant may be contaminated, posing health risks to coking plant workers. Furthermore, our assessment of dietary exposure risk highlights Nap and Fle as the primary dietary contaminants, with BaP and DahA raising concerns due to their higher carcinogenic potential. Our findings indicate that dietary exposure often exceeds acceptable limits, particularly for coking plant workers. Correlation analyses uncover the dominant roles of soil and atmospheric pollution in shaping dietary PAH exposure. Soil contamination significantly impacts specific PAHs, while atmospheric pollution contributes to others. Additionally, WQS regression emphasizes the substantial influence of soil and drinking water on dietary PAHs. In summary, our study sheds light on the dietary exposure characteristics of PAHs in a typical Chinese coking plant and their intricate interplay with environmental factors. These findings underscore the need for comprehensive strategies to mitigate PAH exposure so as to safeguard both human health and the environment in affected regions.
摘要：
多环芳烃(PAHs),以他们的健康风险而闻名，在环境中普遍存在，焦化行业是其排放的主要来源。为了弥合关于环境和饮食PAH暴露之间关系的知识差距，我们通过调查中国典型焦化厂中24种PAHs的膳食暴露特征及其与环境污染的关系来探索这种复杂的相互作用。我们的研究表明，Nap和Fle是主要的饮食污染物，强调土壤和大气污染对PAH暴露的显著影响。我们对数据进行非度量多维缩放(NMDS)，Spearman相关分析,套索回归，和加权分位数和(WQS)回归来深入研究这一多方面的现象。NMDS揭示了膳食PAH暴露，特别是在高分子量（HMW）组中，在焦化厂内部和周围都很常见。这表明在工厂内准备的膳食可能被污染，给焦化厂工人带来健康风险。此外，我们对饮食暴露风险的评估强调Nap和Fle是主要的饮食污染物，BaP和DahA因其更高的致癌潜力而引起关注。我们的研究结果表明，膳食暴露经常超过可接受的限度，特别是焦化厂工人。相关分析揭示了土壤和大气污染在影响膳食PAH暴露中的主导作用。土壤污染显著影响特定的PAHs，而大气污染对其他人有贡献。此外,WQS回归强调土壤和饮用水对膳食PAHs的实质性影响。总之,我们的研究揭示了典型的中国焦化厂PAHs的饮食暴露特征及其与环境因素的复杂相互作用。这些发现强调需要采取综合战略来减少PAH暴露，以保护受影响地区的人类健康和环境。
