Abstract：
Chloramination was commonly used as disinfectant for killing pathogens in water. However, in this process, nitrogen-containing disinfection by-products (N-DBPs) would accidently form and subsequently rise toxicity. Here, we investigated acute toxicity variation and by-products formation during chloramination treatment on UV filter 2-hydroxy-4-methoxy-5-sulfonic acid benzophenone (BP-4). Under alkaline conditions, the acute toxicity of this system had significant increase. A total of 17 transformation products were tentatively identified, and for them, plausible transformation pathways were proposed. Noticeably, numerous aniline and nitrosobenzene analogs were detected, and the dramatic increase of acute toxicity in this system might be primarily attributed to the formation of benzoquinone and aniline analogs. Besides, bromophenol, iodophenol and iodobenzoquinone analogs exhibiting high toxicity were generated in the presence of bromine and iodide ions. This study indicates that chloramination treatment may significantly increase potential health risk, further management on disinfection system is reasonable.
摘要：
氯胺化通常用作消毒剂，用于杀死水中的病原体。然而,在这个过程中,含氮消毒副产物（N-DBP）会意外形成并随后增加毒性。这里,我们研究了紫外线过滤器2-羟基-4-甲氧基-5-磺酸二苯甲酮（BP-4）在氯胺化处理期间的急性毒性变化和副产物形成。在碱性条件下,该系统的急性毒性有显著增加。总共初步确定了17种转化产品,对他们来说,提出了合理的转化途径。值得注意的是，检测到许多苯胺和亚硝基苯类似物，该系统中急性毒性的急剧增加可能主要归因于苯醌和苯胺类似物的形成。此外,溴苯酚,在存在溴和碘离子的情况下产生具有高毒性的碘苯酚和碘苯醌类似物。这项研究表明，氯胺化处理可能会显著增加潜在的健康风险，进一步对消毒制度进行管理是合理的。
