PDF(Pubmed)
Abstract：
UNASSIGNED: To translate and validate an Italian version of the Questionnaire of Olfactory Disorders (IT-QOD).
UNASSIGNED: This is a prospective, multicentre study that involved patients with olfactory dysfunction (OD). Both cases and controls underwent administration of the IT-QOD, Sino-Nasal Outcome Test-22 (SNOT-22) and psychophysical evaluation of orthonasal and retronasal olfactory function.
UNASSIGNED: The IT-QOD was administered to 96 patients and 38 controls. The Cronbach\'s alpha exceeded 0.90, indicating satisfactory internal consistency. The test-retest reliability was found to be high for both parosmia (rs = 0.944) and life quality (rs = 0.969). Patients with OD had significantly higher IT-QOD scores compared to healthy individuals (p < 0.001), indicating strong internal validity. The external validity was also satisfactory, as shown by the significant correlation with SNOT-22 (rs = -0.54) and the threshold, discrimination, and identification score (rs = -0.63).
UNASSIGNED: The IT-QOD was demonstrated to be reliable and valid to assess the impact of OD on the quality of life of Italian-speaking patients.
UNASSIGNED: This is a prospective, multicentre study that involved patients with olfactory dysfunction (OD). Both cases and controls underwent administration of the IT-QOD, Sino-Nasal Outcome Test-22 (SNOT-22) and psychophysical evaluation of orthonasal and retronasal olfactory function.
UNASSIGNED: The IT-QOD was administered to 96 patients and 38 controls. The Cronbach\'s alpha exceeded 0.90, indicating satisfactory internal consistency. The test-retest reliability was found to be high for both parosmia (rs = 0.944) and life quality (rs = 0.969). Patients with OD had significantly higher IT-QOD scores compared to healthy individuals (p < 0.001), indicating strong internal validity. The external validity was also satisfactory, as shown by the significant correlation with SNOT-22 (rs = -0.54) and the threshold, discrimination, and identification score (rs = -0.63).
UNASSIGNED: The IT-QOD was demonstrated to be reliable and valid to assess the impact of OD on the quality of life of Italian-speaking patients.
摘要：
■翻译和验证意大利语版本的嗅觉障碍问卷（IT-QOD）。
■这是一个前景，涉及嗅觉功能障碍（OD）患者的多中心研究。病例和对照均接受了IT-QOD管理，鼻鼻鼻部结果测试-22(SNOT-22)和鼻前和鼻后嗅觉功能的心理物理评估。
■对96名患者和38名对照进行了IT-QOD。克朗巴赫的α值超过0.90，表明内部一致性令人满意。对于假发（rs=0.944）和生活质量（rs=0.969），测试重测可靠性都很高。与健康个体相比，OD患者的IT-QOD评分明显较高（p<0.001），表明内部有效性强。外部有效性也令人满意，如与SNOT-22(rs=-0.54)和阈值的显著相关性所示，歧视,和识别得分(rs=-0.63)。
■IT-QOD被证明是可靠且有效的，可以评估OD对意大利语患者生活质量的影响。
■这是一个前景，涉及嗅觉功能障碍（OD）患者的多中心研究。病例和对照均接受了IT-QOD管理，鼻鼻鼻部结果测试-22(SNOT-22)和鼻前和鼻后嗅觉功能的心理物理评估。
■对96名患者和38名对照进行了IT-QOD。克朗巴赫的α值超过0.90，表明内部一致性令人满意。对于假发（rs=0.944）和生活质量（rs=0.969），测试重测可靠性都很高。与健康个体相比，OD患者的IT-QOD评分明显较高（p<0.001），表明内部有效性强。外部有效性也令人满意，如与SNOT-22(rs=-0.54)和阈值的显著相关性所示，歧视,和识别得分(rs=-0.63)。
■IT-QOD被证明是可靠且有效的，可以评估OD对意大利语患者生活质量的影响。
