{Reference Type}: Multicenter Study
{Title}: Validity and reliability of the Questionnaire of Olfactory Disorders for Italian-speaking patients with olfactory dysfunction.
{Author}: Vaira LA;Tirelli G;Rizzo D;Uderzo F;Avanzini F;Trabalzini F;Rivelli N;Burger D;Calabrese L;Solla P;Bussu F;Mayo-Yáñez M;Lechien JR;De Riu G;Boscolo-Rizzo P;
{Journal}: Acta Otorhinolaryngol Ital
{Volume}: 44
{Issue}: 1
{Year}: 2024 Feb
{Factor}: 2.618
{DOI}: 10.14639/0392-100X-N2736
{Abstract}: <B>UNASSIGNED: </B>To translate and validate an Italian version of the Questionnaire of Olfactory Disorders (IT-QOD).<BR><B>UNASSIGNED: </B>This is a prospective, multicentre study that involved patients with olfactory dysfunction (OD). Both cases and controls underwent administration of the IT-QOD, Sino-Nasal Outcome Test-22 (SNOT-22) and psychophysical evaluation of orthonasal and retronasal olfactory function.<BR><B>UNASSIGNED: </B>The IT-QOD was administered to 96 patients and 38 controls. The Cronbach's alpha exceeded 0.90, indicating satisfactory internal consistency. The test-retest reliability was found to be high for both parosmia (rs = 0.944) and life quality (rs = 0.969). Patients with OD had significantly higher IT-QOD scores compared to healthy individuals (p < 0.001), indicating strong internal validity. The external validity was also satisfactory, as shown by the significant correlation with SNOT-22 (rs = -0.54) and the threshold, discrimination, and identification score (rs = -0.63).<BR><B>UNASSIGNED: </B>The IT-QOD was demonstrated to be reliable and valid to assess the impact of OD on the quality of life of Italian-speaking patients.