PDF(Pubmed)
Abstract：
Canine Parvovirus type 2 (CPV-2) is a highly contagious virus that can cause severe systemic disease with gastroenteric symptoms in dogs, particularly in young puppies. Originating from the feline parvovirus in the late 1970s, it swiftly propagated globally, instigating a pandemic in dogs. Despite vaccination advancements, CPV-2 remains a substantial challenge for veterinary professionals and pet owners. This study aimed to contribute knowledge about the current situation of CPV-2 among dogs in southern Brazil. In this study, the sera of 125 dogs (mostly with gastroenteritis symptoms) were screened for antibodies against CPV-2 and their faeces for the virus itself. The results showed that 40% (50/125) of dogs were infected with CPV-2. Most animals (65.5%) had previously been exposed to CPV-2 (with serotitres equal or above 1:40), and only 37.6% had protective antibody titres equal or above 1:80. The findings have also demonstrated that vaccination against CPV-2 significantly reduced the risk of infection, with positive cases decreasing from 56.9% (unvaccinated) to 2.0% (fully vaccinated). Furthermore, the prevalence of CPV-2 decreased as dogs aged, with younger dogs and those with an incomplete or non-existent vaccination history at the highest risk of infection. In conclusion, this study provides valuable insight into the prevalence and risk factors associated with CPV-2 infection in dogs in southern Brazil, thereby providing valuable knowledge for the improvement of veterinary care and pet health.
摘要：
犬细小病毒2型（CPV-2）是一种高度传染性病毒，可引起严重的全身性疾病，并伴有狗的胃肠道症状，尤其是幼犬。起源于1970年代后期的猫细小病毒，它迅速在全球传播，煽动狗的大流行。尽管疫苗接种取得了进展，CPV-2仍然是兽医专业人员和宠物主人的重大挑战。这项研究旨在帮助了解巴西南部犬中CPV-2的现状。在这项研究中,对125只犬(多数有胃肠炎症状)的血清进行了抗CPV-2抗体的筛查,并对其粪便进行了病毒本身的筛查.结果显示40%(50/125)的犬感染了CPV-2。大多数动物（65.5％）以前曾接触过CPV-2（血清等于或高于1：40），只有37.6%的保护性抗体滴度等于或高于1:80。研究结果还表明，针对CPV-2的疫苗接种显着降低了感染风险，阳性病例从56.9％（未接种疫苗）降至2.0％（完全接种疫苗）。此外，CPV-2的患病率随着狗的年龄而下降，与年轻的狗和那些有不完整或不存在疫苗接种史的人在感染的风险最高。总之,这项研究为巴西南部犬CPV-2感染的患病率和危险因素提供了有价值的见解，从而为改善兽医护理和宠物健康提供有价值的知识。
