METHODS: A systematic search, to January 2023, of Medline, EMBASE, AMED, CINAHL and the Cochrane library was conducted. Studies that reported on adolescents and adults who had been diagnosed with POTS using standard criteria and underwent an exercise-based training intervention were included.
RESULTS: Following full-text screening, 10 articles were identified (2 randomised control trials, 4 comparative studies and 4 case reports). One comparative study reported a small subset of participants with EDS and one case report included an individual diagnosed with CFS; the remainder investigated a wider POTS population. Overall, 3 months of endurance followed by resistance exercise, graduating from the horizontal-to-upright position reduced POTS symptoms and improved quality-of-life.
CONCLUSIONS: The findings highlight a paucity of higher-level studies documenting exercise for POTS management in people with joint hypermobility and related conditions. Results from the wider POTS population demonstrate exercise is safe and effective. Large, well-designed clinical studies exploring exercise for POTS management adapting to meet the complex musculoskeletal and non-musculoskeletal features of symptomatic joint hypermobility are needed.
方法:系统搜索,到2023年1月,Medline,EMBASE,AMED,进行CINAHL和Cochrane文库。研究报告了使用标准标准诊断为POTS并接受基于运动的训练干预的青少年和成年人。
结果:经过全文筛选,确定了10篇文章(2项随机对照试验,4个比较研究和4个病例报告)。一项比较研究报告了一小部分EDS参与者,一项病例报告包括一名被诊断为CFS的个体;其余的调查了更广泛的POTS人群。总的来说,3个月的耐力,然后进行抵抗运动,从水平到直立位置毕业可减少POTS症状并提高生活质量。
结论:研究结果强调了缺乏更高水平的研究,这些研究记录了关节活动过度和相关疾病患者POTS管理的运动。来自更广泛的POTS人群的结果表明运动是安全有效的。大,需要精心设计的临床研究,探索适合POTS管理的运动,以满足症状性关节活动过度的复杂肌肉骨骼和非肌肉骨骼特征。