Abstract：
Sleep deprivation has become increasingly prevalent in contemporary society, and the consequences of this reality such as cognitive impairment and metabolic disorders, are widely investigated in the scientific scenario. However, the impact of sleep deprivation on the health of future generations is a challenge, and researchers are focusing their attention on this issue. Thus, this review aims to describe the impact of sleep deprivation in early life in animal models, particularly rodents, discussing the molecular physiology impacted by prolonged wakefulness in early life, as well as the changes that interfere with neurodevelopmental processes. Additionally, it explores the changes impacting metabolic mechanisms and discusses both the short- and long-term consequences of these processes on endocrine, behavioral, and cognitive functions. Finally, we briefly address some strategies to mitigate the adverse effects of sleep deprivation.
摘要：
睡眠不足在当代社会越来越普遍,以及这种现实的后果，如认知障碍和代谢紊乱，在科学场景中被广泛研究。然而,睡眠不足对后代健康的影响是一个挑战，研究人员将注意力集中在这个问题上。因此，这篇综述旨在描述睡眠剥夺对早期动物模型的影响，尤其是啮齿动物,讨论早年受长期清醒影响的分子生理学，以及干扰神经发育过程的变化。此外,它探讨了影响代谢机制的变化，并讨论了这些过程对内分泌的短期和长期后果，行为，和认知功能。最后,我们简要介绍了一些减轻睡眠剥夺不利影响的策略.
