PDF(Pubmed)
Abstract：
OBJECTIVE: This study aimed to clarify the differences in spine and total body height growth and curve progression between Sanders maturation stage (SMS) 7A and 7B in patients with adolescent idiopathic scoliosis (AIS).
METHODS: This retrospective case-control study involving patients with AIS at SMS 7 evaluated the differential gains in the spine (T1-S1) and total body height and curve progression between SMS 7A and 7B. A validated formula was used to calculate the corrected height, accounting for height loss due to scoliosis. A multivariable non-linear and logistic regression model was applied to assess the distinct growth and curve progression patterns between the SMS 7 subtypes, adjusting for potential confounders.
RESULTS: A total of 231 AIS patients (83% girls, mean age 13.9 ± 1.2 years) were included, with follow-up averaging 3.0 years. Patients at SMS 7A exhibited larger gains in spine height (9.9 mm vs. 6.3 mm) and total body height (19.8 mm vs. 13.4 mm) compared with SMS 7B. These findings remained consistent even after adjustments for curve magnitude. Non-linear regression models showed continued spine and total body height increases plateauing after 2 years, significantly greater in SMS 7A. More SMS 7A patients had curve progression over 10°, with an adjusted odds ratio of 3.31.
CONCLUSIONS: This study revealed that patients staged SMS 7A exhibited more spine and total body growth and a greater incidence of substantial curve progression than those at 7B. These findings imply that delaying brace discontinuation until reaching 7B could be beneficial, particularly for those with larger curves.
METHODS: Level III (Case-control study).
METHODS: This retrospective case-control study involving patients with AIS at SMS 7 evaluated the differential gains in the spine (T1-S1) and total body height and curve progression between SMS 7A and 7B. A validated formula was used to calculate the corrected height, accounting for height loss due to scoliosis. A multivariable non-linear and logistic regression model was applied to assess the distinct growth and curve progression patterns between the SMS 7 subtypes, adjusting for potential confounders.
RESULTS: A total of 231 AIS patients (83% girls, mean age 13.9 ± 1.2 years) were included, with follow-up averaging 3.0 years. Patients at SMS 7A exhibited larger gains in spine height (9.9 mm vs. 6.3 mm) and total body height (19.8 mm vs. 13.4 mm) compared with SMS 7B. These findings remained consistent even after adjustments for curve magnitude. Non-linear regression models showed continued spine and total body height increases plateauing after 2 years, significantly greater in SMS 7A. More SMS 7A patients had curve progression over 10°, with an adjusted odds ratio of 3.31.
CONCLUSIONS: This study revealed that patients staged SMS 7A exhibited more spine and total body growth and a greater incidence of substantial curve progression than those at 7B. These findings imply that delaying brace discontinuation until reaching 7B could be beneficial, particularly for those with larger curves.
METHODS: Level III (Case-control study).
摘要：
目的：本研究旨在阐明青少年特发性脊柱侧凸（AIS）患者Sanders成熟期（SMS）7A和7B之间脊柱和全身高度生长和曲线进展的差异。
方法：这项涉及SMS7AIS患者的回顾性病例对照研究评估了SMS7A和7B之间脊柱（T1-S1）和总体高度和曲线进展的差异。使用经过验证的公式来计算校正高度，考虑脊柱侧弯导致的身高损失。应用多变量非线性和逻辑回归模型来评估SMS7亚型之间的不同生长和曲线进展模式。调整潜在的混杂因素。
结果：总共231例AIS患者（83％的女孩，平均年龄13.9±1.2岁)包括在内，平均随访3.0年。SMS7A患者的脊柱高度增加较大（9.9mmvs.6.3mm）和车身总高度（19.8mm与13.4mm）与SMS7B相比。即使在对曲线大小进行调整之后,这些发现仍然保持一致。非线性回归模型显示2年后脊柱和总身高持续增加，在SMS7A中明显更大。更多SMS7A患者的曲线进展超过10°，调整后的赔率比为3.31。
结论：这项研究显示，与7B阶段的患者相比，SMS7A阶段的患者表现出更多的脊柱和全身生长以及更高的实质性曲线进展发生率。这些发现暗示，延迟支具停药直到达到7B可能是有益的，特别是对于那些曲线较大的人。
方法：III级（病例对照研究）。
方法：这项涉及SMS7AIS患者的回顾性病例对照研究评估了SMS7A和7B之间脊柱（T1-S1）和总体高度和曲线进展的差异。使用经过验证的公式来计算校正高度，考虑脊柱侧弯导致的身高损失。应用多变量非线性和逻辑回归模型来评估SMS7亚型之间的不同生长和曲线进展模式。调整潜在的混杂因素。
结果：总共231例AIS患者（83％的女孩，平均年龄13.9±1.2岁)包括在内，平均随访3.0年。SMS7A患者的脊柱高度增加较大（9.9mmvs.6.3mm）和车身总高度（19.8mm与13.4mm）与SMS7B相比。即使在对曲线大小进行调整之后,这些发现仍然保持一致。非线性回归模型显示2年后脊柱和总身高持续增加，在SMS7A中明显更大。更多SMS7A患者的曲线进展超过10°，调整后的赔率比为3.31。
结论：这项研究显示，与7B阶段的患者相比，SMS7A阶段的患者表现出更多的脊柱和全身生长以及更高的实质性曲线进展发生率。这些发现暗示，延迟支具停药直到达到7B可能是有益的，特别是对于那些曲线较大的人。
方法：III级（病例对照研究）。
