对尿酸单钠晶体的 C 型凝集素受体 CLEC12A 介导的免疫识别的机制见解。
关键词: C-type lectin receptor CLEC12A crystal structure damage-associated molecular pattern monosodium urate crystal oligomerization phagocytic vesicle single-molecule force spectroscopy
Mesh : Humans Gout / metabolism Lectins, C-Type / chemistry immunology Receptors, Mitogen / chemistry immunology Uric Acid / chemistry immunology Protein Domains Crystallography, X-Ray Single Molecule Imaging Cell Line
来 源:
DOI:10.1016/j.jbc.2024.105765
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