Abstract：
A 12-year-old male eclectus parrot (Eclectus roratus) was referred for evaluation of coelomic distention. Computed tomography and blood work revealed coelomic effusion with free coelomic mineral-attenuating material and elevations in the bile acids and aspartate aminotransferase activity, respectively. Coelomic effusion was consistent with macrophagic inflammation with abundant intracellular lipids. Initial treatment with meloxicam resulted in minimal patient improvement. Disseminated xanthogranulomatous inflammation was suspected based on imaging and diagnostic laboratory results, which were consistent with those previously reported. Biopsy samples of liver tissue and intracoelomic masses confirmed this diagnosis. Treatment was initiated with prednisolone 1 mg/kg/d for 6 months, followed by 0.5 mg/kg/d for 3 months. Clinical improvement was assessed based on owner evaluation, plasma bile acid concentrations, and repeated computed tomographic scans. After 2 months of treatment, the owner reported improved behavior and appetite; this persisted throughout treatment and when the bird was reexamined 17 months following the cessation of steroid therapy. Bile acid concentrations were normal 10 months after the prednisolone therapy was discontinued. Diagnostic imaging showed minimal coelomic effusion 10 months after the last prednisolone dose was administered, with improved ventilation of the air sacs and static to improved dystrophic mineral foci. This report describes the antemortem diagnosis and treatment of disseminated coelomic xanthogranulomatous disease in a psittacine species, with an observed measurable therapeutic response.
摘要：
一只12岁的雄性eclectus鹦鹉（Eclectusroratus）被推荐用于评估体腔扩张。计算机断层扫描和血液检查显示，体腔积液具有游离的体腔矿物质衰减物质，胆汁酸和天冬氨酸转氨酶活性升高，分别。腔积液与巨噬细胞炎症一致，细胞内脂质丰富。使用美洛昔康的初始治疗导致最小的患者改善。根据影像学和诊断性实验室结果，怀疑播散性黄色肉芽肿性炎症。这与以前报道的一致。肝组织和肿瘤内肿块的活检样本证实了这一诊断。开始使用泼尼松龙1mg/kg/d治疗6个月，0.5mg/kg/d，连续3个月。根据所有者评估评估临床改善情况，血浆胆汁酸浓度，和重复的计算机断层扫描。治疗2个月后,主人报告行为和食欲改善;这在整个治疗过程中以及在停止类固醇治疗后17个月对鸟类进行重新检查时持续存在。泼尼松龙治疗中断10个月后胆汁酸浓度正常。诊断成像显示在最后一次泼尼松龙给药后10个月出现最小的腔积液，改善了气囊的通风和静态，改善了营养不良的矿物质病灶。本报告描述了一种psittacine物种的播散性体腔黄色肉芽肿病的死前诊断和治疗。观察到可测量的治疗反应。
