PDF(Pubmed)
Abstract：
UNASSIGNED: Schwannoma\'s are benign but clinically progressive tumours. Mostly, they present as intradural extramedullary and as a single lesion. They are quite rare in the intramedullary region and multiple lesions. We report a rare case of Multiple Intramedullary Schwannoma in the thoracic region. The aim of this study to inform an uncommon case of intramedullary schwannoma and support an appropriate preoperative diagnostic.
METHODS: A 43-year-old female patient was admitted with gradual onset weakness of both lower limbs (4/2) for last two months. Magnetic resonance imaging (MRI) scan disclosed an intramedullary tumour at the thoracal 11th and 12th vertebral levels. It measured 30x20x15 mm and 20x20x12 mm. Complete total resection of multiple lesions was done. Schwanoma\'s was confirmed based on the histopathological finding. The patient was discharged on 4th day post operative with both leg power 5/5 and needed to medical rehabilitation. Follow-up examination 1 months after surgery revealed favourable, neurological condition (modified McCormick scale: grade I).
UNASSIGNED: Intramedullary schwannoma is often misdiagnosed as other types of intramedullary tumour. Schwannomas are usually benign and have well defined cleavage plane. Total resection achievable in most cases, offers the best clinical outcome and avoids subsequent recurrence.
CONCLUSIONS: Preoperative diagnosis of intramedullary schwannoma will help establish the optimum medical and surgical treatment and the prognosis. Timely surgery before permanent neurological deficit and gross total resection is recommended to achieve good clinical outcome.
METHODS: A 43-year-old female patient was admitted with gradual onset weakness of both lower limbs (4/2) for last two months. Magnetic resonance imaging (MRI) scan disclosed an intramedullary tumour at the thoracal 11th and 12th vertebral levels. It measured 30x20x15 mm and 20x20x12 mm. Complete total resection of multiple lesions was done. Schwanoma\'s was confirmed based on the histopathological finding. The patient was discharged on 4th day post operative with both leg power 5/5 and needed to medical rehabilitation. Follow-up examination 1 months after surgery revealed favourable, neurological condition (modified McCormick scale: grade I).
UNASSIGNED: Intramedullary schwannoma is often misdiagnosed as other types of intramedullary tumour. Schwannomas are usually benign and have well defined cleavage plane. Total resection achievable in most cases, offers the best clinical outcome and avoids subsequent recurrence.
CONCLUSIONS: Preoperative diagnosis of intramedullary schwannoma will help establish the optimum medical and surgical treatment and the prognosis. Timely surgery before permanent neurological deficit and gross total resection is recommended to achieve good clinical outcome.
摘要：
■神经鞘瘤是良性但临床进行性肿瘤。大多数情况下,它们表现为硬膜内髓外和单个病变。它们在髓内区域和多个病变中非常罕见。我们报告了一例罕见的胸部多发性髓内神经鞘瘤。这项研究的目的是告知罕见的髓内神经鞘瘤病例，并支持适当的术前诊断。
方法：一名43岁的女性患者入院，最近两个月双下肢（4/2）逐渐发作。磁共振成像（MRI）扫描显示胸椎第11和第12椎骨水平的髓内肿瘤。它测量30x20x15毫米和20x20x12毫米。完成了多发性病变的完全切除。根据组织病理学发现证实了Schwanoma。患者在术后第4天出院，腿部力量为5/5，需要进行医疗康复。手术后1个月的随访检查显示良好，神经系统状况（改良麦考密克量表：I级）。
■髓内神经鞘瘤常被误诊为其他类型的髓内肿瘤。神经鞘瘤通常是良性的，并且具有明确的卵裂平面。在大多数情况下可实现的完全切除，提供了最好的临床结果，并避免了随后的复发。
结论：髓内神经鞘瘤的术前诊断有助于确定最佳的内科和外科治疗方法及预后。建议在永久性神经功能缺损和全切前及时手术，以取得良好的临床疗效。
方法：一名43岁的女性患者入院，最近两个月双下肢（4/2）逐渐发作。磁共振成像（MRI）扫描显示胸椎第11和第12椎骨水平的髓内肿瘤。它测量30x20x15毫米和20x20x12毫米。完成了多发性病变的完全切除。根据组织病理学发现证实了Schwanoma。患者在术后第4天出院，腿部力量为5/5，需要进行医疗康复。手术后1个月的随访检查显示良好，神经系统状况（改良麦考密克量表：I级）。
■髓内神经鞘瘤常被误诊为其他类型的髓内肿瘤。神经鞘瘤通常是良性的，并且具有明确的卵裂平面。在大多数情况下可实现的完全切除，提供了最好的临床结果，并避免了随后的复发。
结论：髓内神经鞘瘤的术前诊断有助于确定最佳的内科和外科治疗方法及预后。建议在永久性神经功能缺损和全切前及时手术，以取得良好的临床疗效。
