关键词: Eye Granulomatosis with polyangiitis IgG4 Inflammation MALT lymphoma Orbit Pseudotumor Xanthogranuloma

Mesh : Humans Immunoglobulin G Inflammation Lymphoma Autoimmune Diseases / pathology Immunoglobulin G4-Related Disease / diagnosis

来  源:   DOI:10.1053/j.semdp.2024.01.011

Abstract:
Orbital inflammatory diseases represent a heterogenous group of idiopathic, autoimmune-related, and sometimes neoplastic conditions with overlapping clinical and histopathologic features, as well as variable levels of IgG4-positive plasma cells detected within tissue biopsies. Some histopathologic features, especially in an appropriate clinical context, may point to a specific diagnosis in a given patient. Diagnoses of non-specific orbital inflammation, orbital inflammation related to autoimmune diseases such as granulomatosis with polyangiitis and IgG4-related disease, lymphoma, and xanthogranulomatous diseases are discussed, contrasted and illustrated.
摘要:
眼眶炎性疾病代表特发性的异质性组,自身免疫相关,有时具有重叠的临床和组织病理学特征的肿瘤条件,以及在组织活检中检测到的不同水平的IgG4阳性浆细胞。一些组织病理学特征,尤其是在适当的临床背景下,可能指向特定患者的特定诊断。非特异性眼眶炎症的诊断,眼眶炎症与自身免疫性疾病相关,如肉芽肿性多血管炎和IgG4相关疾病,淋巴瘤并讨论了黄色肉芽肿性疾病,对比和说明。
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