METHODS: Major medical databases such as PubMed, Scopus, Embase, Web of Science, Google Scholar, Cochrane Library, BIOSIS, and EBSCO were searched. The overall search process was conducted in 3 stages.
RESULTS: Finally, a total of 28 studies met the inclusion criteria and were included in this study. Out of those 28 meta-analyses, a total of 315 primary studies were screened in order to extract the data and perform the statistical analysis. In total, data from 22,619 patients was analyzed.
CONCLUSIONS: The main objective of the present umbrella review was to summarize and analyze all of the evidence-based data provided by numerous meta-analyses and systematic reviews regarding the treatment of OPSCC. Our study delivers the most up-to-date and evidence-based results regarding the different therapeutic modalities of this malignancy in one concise review, making it the ultimate tool for physicians treating OPSCC.
方法:主要医疗数据库,如PubMed、Scopus,Embase,WebofScience,谷歌学者,科克伦图书馆,BIOSIS,并对EBSCO进行了搜索。整个搜索过程分3个阶段进行。
结果:最后,共有28项研究符合纳入标准,被纳入本研究.在这28项荟萃分析中,共筛选了315项主要研究,以提取数据并进行统计分析.总的来说,对22,619例患者的数据进行了分析。
结论:本综述的主要目的是总结和分析关于OPSCC治疗的众多荟萃分析和系统综述提供的所有循证数据。我们的研究提供了关于这种恶性肿瘤的不同治疗方式的最新和基于证据的结果,使其成为医生治疗OPSCC的最终工具。