{Reference Type}: Journal Article
{Title}: Treatment options for oropharyngeal carcinoma - An umbrella review.
{Author}: Plutecki D;Szczepanek E;Szczepanek M;Nasser A;Hajdyła P;Wrona A;
{Journal}: Folia Med Cracov
{Volume}: 63
{Issue}: 3
{Year}: 2023 Oct 30
暂无{DOI}: 10.24425/fmc.2023.147217
{Abstract}: <B>BACKGROUND: </B>Our umbrella review aimed to summarize and revisit the evidence from all of the meta-analyses and systematic reviews regarding the treatments of oropharyngeal squamous cell carcinoma (OPSCC).<BR><B>METHODS: </B>Major medical databases such as PubMed, Scopus, Embase, Web of Science, Google Scholar, Cochrane Library, BIOSIS, and EBSCO were searched. The overall search process was conducted in 3 stages.<BR><B>RESULTS: </B>Finally, a total of 28 studies met the inclusion criteria and were included in this study. Out of those 28 meta-analyses, a total of 315 primary studies were screened in order to extract the data and perform the statistical analysis. In total, data from 22,619 patients was analyzed.<BR><B>CONCLUSIONS: </B>The main objective of the present umbrella review was to summarize and analyze all of the evidence-based data provided by numerous meta-analyses and systematic reviews regarding the treatment of OPSCC. Our study delivers the most up-to-date and evidence-based results regarding the different therapeutic modalities of this malignancy in one concise review, making it the ultimate tool for physicians treating OPSCC.