Abstract：
Substance-induced psychosis is a secondary psychotic disorder resulting from drug abuse, characterized by one or more psychotic episodes. Drug-induced psychosis is expected to resolve after a 30-day period of sobriety, however, individuals with this condition are more likely to develop severe drug addiction. Compared to primary psychosis, participants with drug-induced psychosis exhibit poorer family history of psychotic diseases, higher insight, fewer positive and negative symptoms, more depressive symptoms, and greater anxiety. Substance-induced psychosis is strongly associated with the emergence of bipolar illness or schizophrenia spectrum disorder, with an increased chance of developing schizophrenia at a younger age. Episodes of self-harm after substance-induced psychosis are strongly linked to an elevated likelihood of developing schizophrenia or bipolar disorder. Effective treatment involves ruling out emergencies, investigating underlying causes, and addressing acute intoxication and withdrawal. Management includes dynamic assessment, intervention, and vigilant monitoring in cases of suicidal behaviour. Antipsychotics may be used for short term, with gradual discontinuation when a person is in a stable condition. Relapse prevention strategies, both medication and non-medication-based, are crucial in long-term management. Conversion rates to schizophrenia or bipolar disorder can be as high as one in three individuals, with cannabis users and those with early-onset substance abuse at the highest risk.
摘要：
物质诱发的精神病是药物滥用导致的继发性精神病，以一个或多个精神病发作为特征。药物引起的精神病预计在30天的清醒期后会消退，然而,患有这种疾病的人更有可能患上严重的药物成瘾。与原发性精神病相比，药物诱发精神病的参与者表现出较差的精神病家族史，更高的洞察力，阳性和阴性症状较少，更多的抑郁症状，更大的焦虑。物质诱发的精神病与双相情感障碍或精神分裂症谱系障碍的出现密切相关，在更年轻的时候发展为精神分裂症的机会增加。物质诱发的精神病后的自我伤害发作与患精神分裂症或躁郁症的可能性升高密切相关。有效的治疗包括排除紧急情况，调查根本原因，解决急性中毒和戒断。管理包括动态评估，干预，并对自杀行为进行警惕监测。抗精神病药物可以短期使用，当一个人处于稳定状态时逐渐停止。复发预防策略，药物和非药物，在长期管理中至关重要。精神分裂症或躁郁症的转化率可能高达三分之一，大麻使用者和早发性药物滥用者的风险最高。
