Abstract：
OBJECTIVE: The purpose of this study was to compare the tilt and decentration of one-piece anti-vaulting haptic intraocular lenses (IOL) and three-piece C-loop haptic IOLs in paediatric eyes undergoing secondary IOL implantation into the ciliary sulcus.
METHODS: Paediatric aphakic patients receiving either one-piece anti-vaulting haptic or three-piece C-loop haptic IOL implants into the ciliary sulcus were enrolled in this prospective non-randomized interventional study and followed up for 3 years. IOL decentration and tilt were measured using Scheimpflug images. Preoperative and postoperative information, including demographic data and ocular biometric parameters and complications, were collected and analysed.
RESULTS: Among 123 eyes of 79 paediatric patients, there were 72 eyes (58.54%) in the anti-vaulting haptic IOL group and 51 eyes (41.46%) in the C-loop haptic group. The anti-vaulting haptic IOL group had a lower incidence of clinically significant vertical IOL decentration than the C-loop haptic IOL group (23.88% vs. 43.14%, p = 0.037). No intergroup differences were observed in vertical or horizontal tilt or in horizontal decentration (all p > 0.05). One-piece anti-vaulting haptic IOL implantation was associated with a lower risk of clinically significant vertical decentration than three-piece C-loop haptic IOL implantation (odds ratio: 0.42, p = 0.037). There was a higher incidence of IOL dislocation in the C-loop haptic IOL group (15.22% vs. 4.17%, p = 0.046).
CONCLUSIONS: In paediatric aphakic eyes undergoing secondary IOL implantation into the ciliary sulcus, one-piece anti-vaulting haptic IOLs can reduce the risk of clinically significant vertical IOL decentration compared with three-piece C-loop haptic IOLs and may favour long-term IOL positional stability.
METHODS: Paediatric aphakic patients receiving either one-piece anti-vaulting haptic or three-piece C-loop haptic IOL implants into the ciliary sulcus were enrolled in this prospective non-randomized interventional study and followed up for 3 years. IOL decentration and tilt were measured using Scheimpflug images. Preoperative and postoperative information, including demographic data and ocular biometric parameters and complications, were collected and analysed.
RESULTS: Among 123 eyes of 79 paediatric patients, there were 72 eyes (58.54%) in the anti-vaulting haptic IOL group and 51 eyes (41.46%) in the C-loop haptic group. The anti-vaulting haptic IOL group had a lower incidence of clinically significant vertical IOL decentration than the C-loop haptic IOL group (23.88% vs. 43.14%, p = 0.037). No intergroup differences were observed in vertical or horizontal tilt or in horizontal decentration (all p > 0.05). One-piece anti-vaulting haptic IOL implantation was associated with a lower risk of clinically significant vertical decentration than three-piece C-loop haptic IOL implantation (odds ratio: 0.42, p = 0.037). There was a higher incidence of IOL dislocation in the C-loop haptic IOL group (15.22% vs. 4.17%, p = 0.046).
CONCLUSIONS: In paediatric aphakic eyes undergoing secondary IOL implantation into the ciliary sulcus, one-piece anti-vaulting haptic IOLs can reduce the risk of clinically significant vertical IOL decentration compared with three-piece C-loop haptic IOLs and may favour long-term IOL positional stability.
摘要：
目的：本研究的目的是比较在接受二次IOL植入睫状沟的儿科眼睛中，单件式抗拱顶触觉人工晶状体（IOL）和三件式C环触觉人工晶状体的倾斜和偏心。
方法：这项前瞻性非随机介入研究招募了接受一件式抗跳脱触觉或三件式C环触觉IOL植入睫状沟的小儿无晶状体患者，并随访3年。使用Scheimpflug图像测量IOL偏心和倾斜。术前和术后信息，包括人口统计数据和眼部生物参数和并发症，进行了收集和分析。
结果：在79名儿科患者的123只眼中，抗跳跃触觉IOL组72眼(58.54%),C-loop触觉组51眼(41.46%)。与C-loop触觉IOL组相比，抗跳跃触觉IOL组的临床上显着的垂直IOL分散发生率较低（23.88％vs.43.14%,p=0.037)。在垂直或水平倾斜或水平偏心方面未观察到组间差异（均p>0.05）。与三片C-loop触觉IOL植入相比，单片式抗拱顶触觉IOL植入与临床上明显的垂直偏心风险较低相关（比值比：0.42，p=0.037）。C-loop触觉IOL组的IOL脱位发生率较高（15.22％vs.4.17%，p=0.046)。
结论：在接受二次IOL植入睫状沟的小儿无晶状体眼，与三片C环触觉IOL相比,单片式抗跳跃触觉IOL可降低临床上显著的垂直IOL偏心的风险,并且可能有利于IOL的长期位置稳定性.
方法：这项前瞻性非随机介入研究招募了接受一件式抗跳脱触觉或三件式C环触觉IOL植入睫状沟的小儿无晶状体患者，并随访3年。使用Scheimpflug图像测量IOL偏心和倾斜。术前和术后信息，包括人口统计数据和眼部生物参数和并发症，进行了收集和分析。
结果：在79名儿科患者的123只眼中，抗跳跃触觉IOL组72眼(58.54%),C-loop触觉组51眼(41.46%)。与C-loop触觉IOL组相比，抗跳跃触觉IOL组的临床上显着的垂直IOL分散发生率较低（23.88％vs.43.14%,p=0.037)。在垂直或水平倾斜或水平偏心方面未观察到组间差异（均p>0.05）。与三片C-loop触觉IOL植入相比，单片式抗拱顶触觉IOL植入与临床上明显的垂直偏心风险较低相关（比值比：0.42，p=0.037）。C-loop触觉IOL组的IOL脱位发生率较高（15.22％vs.4.17%，p=0.046)。
结论：在接受二次IOL植入睫状沟的小儿无晶状体眼，与三片C环触觉IOL相比,单片式抗跳跃触觉IOL可降低临床上显著的垂直IOL偏心的风险,并且可能有利于IOL的长期位置稳定性.
