PDF(Pubmed)
Abstract：
BACKGROUND: Mpox is a viral illness with a characteristic skin rash caused by the monkeypox virus. In 2022, Mpox spread throughout the world, and an epidemic through domestic transmission started in South Korea in early 2023. This study aimed to summarize the clinical features of Mpox patients in South Korea.
METHODS: This is a multicenter retrospective study conducted at four hospitals in South Korea. All adult patients diagnosed with Mpox who were admitted to the study hospitals between June 1, 2022 and May 26, 2023 and were discharged by June 30, 2023 were reviewed.
RESULTS: Sixty patients were included, accounting for 65.9% of Mpox cases reported in South Korea during the study period. Median age was 32 years and 97% (58/60) of patients were male. In total, 85% (51/60) of patients reported their sexual orientation as homosexual or bisexual. The most common route of transmission was sexual or close contact (55/60). Every patient had a skin rash and 88% (53/60) had constitutional symptoms. In total, 42% (25/60) of patients had human immunodeficiency virus and 25% (15/60) had concomitant sexually transmitted infections. Severe manifestations of Mpox were identified in only two patients.
CONCLUSIONS: Mpox patients in South Korea were mainly young adult males and were infected through sexual contact. The clinical outcomes were favorable.
METHODS: This is a multicenter retrospective study conducted at four hospitals in South Korea. All adult patients diagnosed with Mpox who were admitted to the study hospitals between June 1, 2022 and May 26, 2023 and were discharged by June 30, 2023 were reviewed.
RESULTS: Sixty patients were included, accounting for 65.9% of Mpox cases reported in South Korea during the study period. Median age was 32 years and 97% (58/60) of patients were male. In total, 85% (51/60) of patients reported their sexual orientation as homosexual or bisexual. The most common route of transmission was sexual or close contact (55/60). Every patient had a skin rash and 88% (53/60) had constitutional symptoms. In total, 42% (25/60) of patients had human immunodeficiency virus and 25% (15/60) had concomitant sexually transmitted infections. Severe manifestations of Mpox were identified in only two patients.
CONCLUSIONS: Mpox patients in South Korea were mainly young adult males and were infected through sexual contact. The clinical outcomes were favorable.
摘要：
背景：水痘是一种由猴痘病毒引起的特征性皮疹的病毒性疾病。2022年，水痘在世界各地蔓延，2023年初，韩国开始了通过国内传播的流行病。本研究旨在总结韩国水痘患者的临床特点。
方法：这是一项在韩国四家医院进行的多中心回顾性研究。对2022年6月1日至2023年5月26日期间入住研究医院并于2023年6月30日出院的所有诊断为Mpox的成年患者进行了审查。
结果：纳入60例患者，占研究期间韩国报告的水痘病例的65.9%。中位年龄为32岁，97%(58/60)的患者为男性。总的来说,85％（51/60）的患者报告其性取向为同性恋或双性恋。最常见的传播途径是性或密切接触（55/60）。每个患者都有皮疹，88％（53/60）有全身症状。总的来说,42％（25/60）的患者患有人类免疫缺陷病毒，25％（15/60）的患者伴有性传播感染。仅在两名患者中发现了严重的水痘表现。
结论：韩国的水痘患者主要是年轻的成年男性，通过性接触感染。临床结果良好。
方法：这是一项在韩国四家医院进行的多中心回顾性研究。对2022年6月1日至2023年5月26日期间入住研究医院并于2023年6月30日出院的所有诊断为Mpox的成年患者进行了审查。
结果：纳入60例患者，占研究期间韩国报告的水痘病例的65.9%。中位年龄为32岁，97%(58/60)的患者为男性。总的来说,85％（51/60）的患者报告其性取向为同性恋或双性恋。最常见的传播途径是性或密切接触（55/60）。每个患者都有皮疹，88％（53/60）有全身症状。总的来说,42％（25/60）的患者患有人类免疫缺陷病毒，25％（15/60）的患者伴有性传播感染。仅在两名患者中发现了严重的水痘表现。
结论：韩国的水痘患者主要是年轻的成年男性，通过性接触感染。临床结果良好。
