PDF(Pubmed)
Abstract：
Hemorrhagic fever with renal syndrome (HFRS) is caused by hantaviruses (HVs) and is endemic in Zhejiang Province, China. In this study, we aimed to explore the changing epidemiology of HFRS cases and the dynamics of hantavirus hosts in Zhejiang Province. Joinpoint regression was used to analyze long-term trends in the incidence of HFRS. The comparison of animal density at different stages was conducted using the Mann-Whitney Test. A comparison of HV carriage rates between stages and species was performed using the chi-square test. The incidence of HFRS shows a continuous downward trend. Cases are widely distributed in all counties of Zhejiang Province except Shengsi County. There was a high incidence belt from west to east, with low incidence in the south and north. The HFRS epidemic showed two seasonal peaks in Zhejiang Province, which were winter and summer. It showed a marked increase in the age of the incidence population. A total of 23,073 minibeasts from 21 species were captured. Positive results were detected in the lung tissues of 14 rodent species and 1 shrew species. A total of 80% of the positive results were from striped field mice and brown rats. No difference in HV carriage rates between striped field mice and brown rats was observed (χ2 = 0.258, p = 0.611).
摘要：
肾综合征出血热（HFRS）是由汉坦病毒（HVs）引起的，在浙江省流行，中国。在这项研究中,我们旨在探讨浙江省HFRS病例的流行病学变化和汉坦病毒宿主的动态。采用Joinpoint回归分析HFRS发病率的长期趋势。使用Mann-Whitney测试对不同阶段的动物密度进行比较。使用卡方检验比较了阶段和物种之间的HV携带率。HFRS发病率呈持续下降趋势。病例广泛分布于浙江省各县,但盛思县除外。从西向东有一个高发带，南方和北方发病率低。浙江省HFRS疫情呈现两个季节性高峰,那是冬天和夏天。它显示发病率人群的年龄显着增加。总共捕获了来自21个物种的23,073只小型野兽。在14种啮齿动物和1种rew的肺组织中检测到阳性结果。共有80％的阳性结果来自条纹田鼠和棕色大鼠。在条纹野外小鼠和棕色大鼠之间没有观察到HV携带率的差异(χ2=0.258,p=0.611)。
