Abstract:
The biochemistry of diabetes mellitus results in multi-system tissue compromise that reduces functional mobility and interferes with disease management. Sensory system compromise, such as peripheral neuropathy and retinopathy, are specific examples of tissue compromise detrimental to functional mobility. There is lack of clarity regarding if, when, and where parallel changes in the peripheral vestibular system, an additional essential sensory system for functional mobility, occur as a result of diabetes. Given the systemic nature of diabetes and the plasticity of the vestibular system, there is even less clarity regarding if potential vestibular system changes impact functional mobility in a meaningful fashion. This commentary will provide insight as to when we should employ diagnostic vestibular function tests in people with diabetes, where in the periphery we should look, and why testing may or may not matter. The commentary concludes with recommendations for future research and clinical care.
摘要:
糖尿病的生物化学导致多系统组织受损,从而降低功能移动性并干扰疾病管理。感官系统妥协,如周围神经病变和视网膜病变,是对功能移动性有害的组织损害的具体例子。关于如果,when,周围前庭系统的平行变化,一个额外的必要的感官系统的功能流动性,由于糖尿病而发生。鉴于糖尿病的系统性和前庭系统的可塑性,对于潜在的前庭系统变化是否以有意义的方式影响功能移动性,甚至还不太清楚。这篇评论将提供我们何时应该对糖尿病患者进行诊断性前庭功能测试的见解,我们应该看看外围的地方,以及为什么测试可能或可能无关紧要。评论最后提出了对未来研究和临床护理的建议。