PDF(Pubmed)
Abstract：
Myxobacteria have a complex life cycle and unique social behavior, and obtain nutrients by preying on bacteria and fungi in soil. Chitinase, β-1,3 glucanase and β-1,6 glucanase produced by myxobacteria can degrade the glycosidic bond of cell wall of some plant pathogenic fungi, resulting in a perforated structure in the cell wall. In addition, isooctanol produced by myxobacteria can lead to the accumulation of intracellular reactive oxygen species in some pathogenic fungi and induce cell apoptosis. Myxobacteria can also perforate the cell wall of some plant pathogenic oomycetes by β-1,3 glucanase, reduce the content of intracellular soluble protein and protective enzyme activity, affect the permeability of oomycete cell membrane, and aggravate the oxidative damage of pathogen cells. Small molecule compounds such as diisobutyl phthalate and myxovirescin produced by myxobacteria can inhibit the formation of biofilm and lipoprotein of bacteria, and cystobactamids can inhibit the activity of DNA gyrase, thus changing the permeability of bacterial cell membrane. Myxobacteria, as a new natural compound resource bank, can control plant pathogenic fungi, oomycetes and bacteria by producing carbohydrate active enzymes and small molecular compounds, so it has great potential in plant disease control.
摘要：
粘细菌具有复杂的生命周期和独特的社会行为，并通过捕食土壤中的细菌和真菌来获取养分。几丁质酶,粘细菌产生的β-1,3葡聚糖酶和β-1,6葡聚糖酶可以降解某些植物病原真菌细胞壁的糖苷键，导致细胞壁中的穿孔结构。此外,粘细菌产生的异辛醇可导致某些病原真菌细胞内活性氧的积累，并诱导细胞凋亡。粘细菌还可以通过β-1,3葡聚糖酶穿透某些植物病原卵菌的细胞壁，降低细胞内可溶性蛋白的含量和保护酶的活性，影响卵菌细胞膜的通透性，并加重病原细胞的氧化毁伤。粘细菌产生的邻苯二甲酸二异丁酯、粘蛋白等小分子化合物可抑制细菌生物膜和脂蛋白的形成,和囊虫毒素可以抑制DNA促旋酶的活性，从而改变细菌细胞膜的通透性。粘细菌,作为一种新的天然复合资源库,可以控制植物病原真菌，卵菌和细菌通过产生碳水化合物活性酶和小分子化合物，所以它在植物病害防治方面有很大的潜力。
