Abstract：
OBJECTIVE: To compare the safety and performance clinical outcomes of the 27-gauge (G) two-dimensional cutting vitrectomy probe versus a standard 25-G probe for retinal procedures.
METHODS: In this large randomized prospective study, all candidates for epiretinal membrane or macular hole surgery were randomized to the 27-G group or 25-G group. Outcome measures included surgery time, changes in best-corrected distance visual acuity, intraocular pressure, and central macular thickness between baseline and 1-month and 3-month follow-up time points. Moreover, intraoperative and postoperative complications were evaluated as well as the rate of sutureless vitrectomy.
RESULTS: A total of 463 patients were included in this study, 227 patients in the 27-G group and 236 patients in the 25-G group. A similar total surgery time was found between both groups ( P = 0.0911). Similar best-corrected distance visual acuity and central macular thickness changes were observed between baseline and the 1-month and 3-month follow-up visits. No significant differences were reported in intraoperative and postoperative complications rates. The rate of sutureless vitrectomy was 96.5% for the 27-G group and 91.1% for the 25-G group ( P = 0.0170).
CONCLUSIONS: These results suggest that 27-G vitrectomy probe is similar to 25-G probe in surgery time and complications, while decreasing the need for vitrectomy sutures.
METHODS: In this large randomized prospective study, all candidates for epiretinal membrane or macular hole surgery were randomized to the 27-G group or 25-G group. Outcome measures included surgery time, changes in best-corrected distance visual acuity, intraocular pressure, and central macular thickness between baseline and 1-month and 3-month follow-up time points. Moreover, intraoperative and postoperative complications were evaluated as well as the rate of sutureless vitrectomy.
RESULTS: A total of 463 patients were included in this study, 227 patients in the 27-G group and 236 patients in the 25-G group. A similar total surgery time was found between both groups ( P = 0.0911). Similar best-corrected distance visual acuity and central macular thickness changes were observed between baseline and the 1-month and 3-month follow-up visits. No significant differences were reported in intraoperative and postoperative complications rates. The rate of sutureless vitrectomy was 96.5% for the 27-G group and 91.1% for the 25-G group ( P = 0.0170).
CONCLUSIONS: These results suggest that 27-G vitrectomy probe is similar to 25-G probe in surgery time and complications, while decreasing the need for vitrectomy sutures.
摘要：
目的：比较用于视网膜手术的27号（G）二维切割玻璃体切除术探针与标准25-G探针的安全性和性能临床结果。
方法：在这项大型随机前瞻性研究中，所有接受视网膜前膜或黄斑孔手术的患者被随机分为27-G组或25-G组.结果指标包括手术时间，最佳矫正视力(BCDVA)的变化，眼内压（IOP），基线和1个月和3个月随访时间点之间的中央黄斑厚度（CMT）。此外，评估术中和术后并发症以及无缝合玻璃体切除术的发生率。
结果：本研究共纳入463例患者，27-G组227例，25-G组236例。两组之间的总手术时间相似（p=0.0911）。在基线和1-和3-mont随访之间观察到类似的BCDVA和CMT变化。在术中和术后并发症发生率方面没有显着差异。27-G组的无缝线玻璃体切除术率为96.5％，25-G组为91.1％（p=0.0170）。
结论：这些结果表明，在手术时间和并发症方面，27-G玻璃体切割探针与25-G探针相似，同时减少对玻璃体切割缝合的需要。
方法：在这项大型随机前瞻性研究中，所有接受视网膜前膜或黄斑孔手术的患者被随机分为27-G组或25-G组.结果指标包括手术时间，最佳矫正视力(BCDVA)的变化，眼内压（IOP），基线和1个月和3个月随访时间点之间的中央黄斑厚度（CMT）。此外，评估术中和术后并发症以及无缝合玻璃体切除术的发生率。
结果：本研究共纳入463例患者，27-G组227例，25-G组236例。两组之间的总手术时间相似（p=0.0911）。在基线和1-和3-mont随访之间观察到类似的BCDVA和CMT变化。在术中和术后并发症发生率方面没有显着差异。27-G组的无缝线玻璃体切除术率为96.5％，25-G组为91.1％（p=0.0170）。
结论：这些结果表明，在手术时间和并发症方面，27-G玻璃体切割探针与25-G探针相似，同时减少对玻璃体切割缝合的需要。
