PDF(Pubmed)
Abstract：
The eucalyptus tree is an excellent source of antimicrobial agents; it is used in many oral cure products. The bitter taste of these agents could compromise their usage. Therefore, fortifying the extracts with non-nutritive sweeteners could be a promising procedure for masking their unpleasant taste. This study was an in vitro evaluation of the antimicrobial activity of eucalyptus (alcoholic and aqueous) extracts against salivary Streptococci mutans. It aimed to investigate the effect of non-nutritive sweeteners on the antimicrobial activity of these extracts against salivary S. mutans. The test microbes were sensitive to different concentrations of eucalyptus alcoholic and aqueous extract, and the inhibition zone increased as the concentration of the extracts increased. All the Mutans isolates were killed at a concentration of 75 mg/ml for the alcoholic extract and 175 mg/ml for the aqueous extracts. In this experiment, the concentration of up to 15% stevia and up to 5% sucralose did not affect the antimicrobial activity of eucalyptus alcoholic extract. While the concentration of up to 1% of stevia and sucralose did not interfere with the antimicrobial activity of aqueous eucalyptus extract against salivary S. mutans. An increase in the concentration of non-nutritive sweeteners in this experiment appeared to interfere with the antimicrobial activity of eucalyptus extract against salivary S. mutans.
摘要：
桉树是抗微生物剂的极好来源;它用于许多口服治疗产品。这些试剂的苦味可能损害它们的使用。因此,用非营养性甜味剂强化提取物可能是掩盖其令人不快味道的有前途的程序。这项研究是对桉树（酒精和水）提取物对唾液变形链球菌的抗菌活性的体外评估。目的研究非营养性甜味剂对这些提取物抗唾液变形链球菌的抗菌活性的影响。试验微生物对不同浓度的桉树醇提液和水提液敏感,并且抑制区随着提取物浓度的增加而增加。所有突变分离物的醇提取物浓度为75mg/ml,水提取物浓度为175mg/ml。在这个实验中,浓度高达15％的甜叶菊和高达5％的三氯蔗糖不影响桉树醇提取物的抗菌活性。而高达1%的甜叶菊和三氯半乳蔗糖的浓度不会干扰水性桉树提取物对唾液变形链球菌的抗微生物活性。在该实验中,非营养性甜味剂浓度的增加似乎干扰了桉树提取物对唾液变形链球菌的抗微生物活性。
