Abstract：
OBJECTIVE: To measure and compare the serum levels of resistin and lipid profile parameters in primigravida females with and without preeclampsia.
UNASSIGNED: The analytical cross-sectional study was conducted at the Department of Physiology and Cell Biology, University of Health Sciences, Lahore, Pakistan, from 2018 to 2020, and comprised primigravida females having gestational age 30-36 weeks. Those with preeclampsia constituted group 1, while normotensive females constituted group 2. All the participants were subjected to detailed history and general physical examination. Serum resistin levels were measured by enzymelinked immunosorbent assay, and lipid profile parameters were measured using the colorimetric method. Data was analysed using SPSS 20.
RESULTS: Of the 80 women, 40(50%) were in group 1 with mean age 23.07±2.10 years and mean gestation age 33.45±2.30 weeks. There were 40(50%) women in group 2 with mean age 23.02±2.11 years and mean gestational age 34.45±1.75 weeks. Mean serum resistin was significantly higher in group 1 compared to group 2 (p<0.02). Mean levels of lipid parameters were significantly different between the groups (p˂0.05).
UNASSIGNED: Preeclampsia was found to be associated with higher levels of resistin and lipid parameters compared to normal pregnancy.
UNASSIGNED: The analytical cross-sectional study was conducted at the Department of Physiology and Cell Biology, University of Health Sciences, Lahore, Pakistan, from 2018 to 2020, and comprised primigravida females having gestational age 30-36 weeks. Those with preeclampsia constituted group 1, while normotensive females constituted group 2. All the participants were subjected to detailed history and general physical examination. Serum resistin levels were measured by enzymelinked immunosorbent assay, and lipid profile parameters were measured using the colorimetric method. Data was analysed using SPSS 20.
RESULTS: Of the 80 women, 40(50%) were in group 1 with mean age 23.07±2.10 years and mean gestation age 33.45±2.30 weeks. There were 40(50%) women in group 2 with mean age 23.02±2.11 years and mean gestational age 34.45±1.75 weeks. Mean serum resistin was significantly higher in group 1 compared to group 2 (p<0.02). Mean levels of lipid parameters were significantly different between the groups (p˂0.05).
UNASSIGNED: Preeclampsia was found to be associated with higher levels of resistin and lipid parameters compared to normal pregnancy.
摘要：
目的：测量和比较患有和未患有先兆子痫的初产妇的血清抵抗素水平和血脂参数。
■分析性横断面研究是在生理学和细胞生物学系进行的，健康科学大学,拉合尔,巴基斯坦,从2018年到2020年，包括胎龄30-36周的primigravida女性。先兆子痫患者构成第1组，而血压正常的女性构成第2组。所有参与者都接受了详细的病史和一般体检。采用酶联免疫吸附试验测定血清抵抗素水平,和脂质分布参数使用比色法测量。使用SPSS20对数据进行分析。
结果：在80名女性中，第1组40例（50％），平均年龄23.07±2.10岁，平均孕龄33.45±2.30周。第2组中有40名（50％）妇女，平均年龄23.02±2.11岁，平均胎龄34.45±1.75周。与第2组相比，第1组的平均血清抵抗素明显更高（p<0.02）。各组间血脂参数的平均水平有显著差异(p<0.05)。
■与正常妊娠相比，子痫前期与较高水平的抵抗素和脂质参数有关。
■分析性横断面研究是在生理学和细胞生物学系进行的，健康科学大学,拉合尔,巴基斯坦,从2018年到2020年，包括胎龄30-36周的primigravida女性。先兆子痫患者构成第1组，而血压正常的女性构成第2组。所有参与者都接受了详细的病史和一般体检。采用酶联免疫吸附试验测定血清抵抗素水平,和脂质分布参数使用比色法测量。使用SPSS20对数据进行分析。
结果：在80名女性中，第1组40例（50％），平均年龄23.07±2.10岁，平均孕龄33.45±2.30周。第2组中有40名（50％）妇女，平均年龄23.02±2.11岁，平均胎龄34.45±1.75周。与第2组相比，第1组的平均血清抵抗素明显更高（p<0.02）。各组间血脂参数的平均水平有显著差异(p<0.05)。
■与正常妊娠相比，子痫前期与较高水平的抵抗素和脂质参数有关。
